Results 161 to 170 of about 1,194,513 (315)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Algumas considerações sobre a utilização de modalidades terapêuticas não tradicionais pelo enfermeiro na assistência de enfermagem psiquiátrica Algunas consideraciones sobre la utilización de modalidades terapeúticas no tradicionales por el enfermero en la atención de enfermería psiquiátrica Some considerations about nurses' use of non traditional therapies in psychiatric nursing care

open access: yesRevista Latino-Americana de Enfermagem, 2005
Neste trabalho, uma revisão da literatura foi realizada com o objetivo de identificar trabalhos que descrevessem modalidades terapêuticas não tradicionais que o enfermeiro psiquiátrico tem capacidade para utilizar em sua prática diária.
Rubia Laine de Paula Andrade   +1 more
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Sucrose, Motor Activity, and Learning

open access: yesPediatric Neurology Briefs, 1988
The effects of sugar (sucrose) on the behavior of 30 preschool children (20 boys and 10 girls, mean age 5 years 4 mos) and 15 elementary school children (6 boys and 9 girls, mean age 7 yrs 2 mos) were investigated by psychologists from Colorado State University, Fort Collins, CO, and the Univ of Mississippi Med Cntr, Jackson, MS.
openaire   +4 more sources

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Questionários indicam um baixo efeito global do nível de atividade física e do controle do estresse sobre o perfil lipídico de homens.

open access: yesRevista Brasileira de Cineantropometria e Desempenho Humano, 2013
Objetivou-se verificar se o perfil lipídico (PL) difere entre homens classificados em duas categorias de nível de atividade física (NAF) e de controle do estresse; e, analisar os resultados à luz das evidências que apontam relação inversa entre NAF, PL e
Maria Fátima Glaner
doaj   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Sport e Sviluppo Sociale: Modelli a Confronto

open access: yesFormazione & Insegnamento
Questo studio si addentra nell’esplorazione dello sviluppo sociale attraverso lo sport analizzando tre modelli distinti provenienti da Italia, Finlandia e Brasile.
Matteo Giuriato
doaj  

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