Hibernation reduces GABA signaling in the brainstem to enhance motor activity of breathing at cool temperatures. [PDF]
Saunders SE, Santin JM.
europepmc +1 more source
PINK1 and Parkin Ameliorate the Loss of Motor Activity and Mitochondrial Dysfunction Induced by Peripheral Neuropathy-Associated HSPB8 Mutants in Drosophila Models. [PDF]
Kang KH+8 more
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
A novel ADP-directed chaperone function facilitates the ATP-driven motor activity of SARS-CoV helicase. [PDF]
Yu J+5 more
europepmc +1 more source
The development of hindlimb motor activity studied in the isolated spinal cord of the chick embryo [PDF]
Michael J. O’Donovan+1 more
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Validade e fidedignidade da escala de satisfação com a prática de atividade física em adultos
OBJETIVO: Analisar a validade, a consistência interna e a fidedignidade da escala de satisfação com a prática de atividade física em adultos brasileiros.
Cassiano Ricardo Rech+3 more
doaj
Influence of native thin filament type on the regulation of atrial and ventricular myosin motor activity. [PDF]
Spahiu E+4 more
europepmc +1 more source
How much prestin motor activity is required for normal hearing? [PDF]
Homma K, Takahashi S, Cheatham MA.
europepmc +1 more source