Results 211 to 220 of about 11,248,254 (342)

EFFECT OF ANTIBIOTICS ON THE URETER MOTOR ACTIVITY

open access: gold, 1973
G. Benzi   +5 more
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Validade e fidedignidade da escala de satisfação com a prática de atividade física em adultos

open access: yesRevista de Saúde Pública
OBJETIVO: Analisar a validade, a consistência interna e a fidedignidade da escala de satisfação com a prática de atividade física em adultos brasileiros.
Cassiano Ricardo Rech   +3 more
doaj  

How much prestin motor activity is required for normal hearing? [PDF]

open access: yesHear Res, 2022
Homma K, Takahashi S, Cheatham MA.
europepmc   +1 more source

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