Results 211 to 220 of about 7,308,492 (309)

Involvement of the Endothelial <i>N</i>-Methyl-d-Aspartate Receptor on Vessel-Associated Positioning and Differentiation of Cortical Oligodendrocytes and on Motor Activity. [PDF]

J Neurosci
Beranger A, Lafenêtre M, Lacomme S, Lebon A, Genty D, Brosolo M, Janin F, Leroy A, Guérout N, Vivien D, Galas L, Marret S, Marguet F, Gontier E, Gonzalez BJ, Lecointre M.   +15 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

5-HT_1A receptor antagonism decreases motor activity and influences dopamine and serotonin metabolization pathways, primarily in cingulate cortex and striatum. [PDF]

Sci Rep
Fazari B, Nikolaus S, Chao OY, Almeida FR, Abdel-Hafiz L, Beu M, Henke J, Antke C, Mamlins E, Hautzel H, Müller HW, Huston JP, von Gall C, Giesel FL.   +13 more
europepmc   +1 more source

Photochemically Activated Motors

Self-propelled micro/nanomotors that can transform chemical energy from the surrounding environment into mechanical motion are cutting edge nanotechnologies with potential applications in biomedicine and environmental remediation. These applications require full understanding of the propulsion mechanisms to improve the performance and controllability ...
Zhang, Kuan, Fraxedas, Jordi||, Sepúlveda, Borja||, Esplandiu Egido, Maria José||   +3 more
openaire   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Multimodal driver emotion recognition using motor activity and facial expressions. [PDF]

Front Artif Intell
Espino-Salinas CH, Luna-García H, Celaya-Padilla JM, Barría-Huidobro C, Gamboa Rosales NK, Rondon D, Villalba-Condori KO.   +6 more
europepmc   +1 more source

Activation of Motor Fuels [PDF]

Global Journal of Engineering Sciences, 2019
openaire   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

OBF-Psychiatric, a motor activity dataset of patients diagnosed with major depression, schizophrenia, and ADHD. [PDF]

Sci Data
Garcia-Ceja E, Stautland A, Riegler MA, Halvorsen P, Hinojosa S, Ochoa-Ruiz G, Berle JO, Førland W, Mjeldheim K, Oedegaard KJ, Jakobsen P.   +10 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source