Results 241 to 250 of about 1,194,513 (315)

EFFECT OF ANTIBIOTICS ON THE URETER MOTOR ACTIVITY

, 1973
G. Benzi, E. Arrigoni, P. PANCERT, R. Panzarasa, F. Bertè, A. Crema   +5 more
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Biphasic effects of intra‐accumbens histamine administration on spontaneous motor activity in the rat; a role for central histamine receptors [PDF]

, 1988
Linda J. Bristow, G.W. Bennett
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Effects of osmoreceptor stimulation on human duodenal motor activity. [PDF]

, 1988
David G. Thompson, D L Wingate
openalex   +1 more source

MIF as an oncogenic driver of low‐heterogeneity melanomas

Molecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran, Gabriela Athziri Sánchez‐Zuno, Rajan P. Kulkarni, Harriet M. Kluger, Richard Bucala   +4 more
wiley   +1 more source

Use of accelerometry to measure physical activity in adults and the elderly

Revista de Saúde Pública
OBJECTIVE: To review the use of accelerometry as an objective measure of physical activity in adults and elderly people. METHODS: A systematic review of studies on the use of accelerometty as an objective measure to assess physical activity in adults ...
Teresa Bento, António Cortinhas, José Carlos Leitão, Maria Paula Mota   +3 more
doaj  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Effects of secretin on the canine duodenal (D) pancreatic duct (PD) and pancreatic sphincter yield (SY) pressures (P) and duodenal motor activity fronts (AF)

, 1978
E.P. DiMagno, J. C. Hendricks, Roger R. Dozois, V.L.W. Go   +3 more
openalex   +1 more source

ORAL HYOSCINE BUTYLBROMIDE DOES NOT ALTER THE PATTERN OF SMALL INTESTINAL MOTOR ACTIVITY [PDF]

, 1981
David G. Thompson, D. L. Wingate
openalex   +1 more source