Results 251 to 260 of about 1,194,513 (315)
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Invariance of Oscillator Interneurone Activity During Variable Motor Output by Locusts [PDF]
, 1989 Heinrich Reichert, C. H. F. Rowell
openalex +1 more source
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Molecular Oncology, EarlyView.Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
Motor Activity in the Stump of an Amputated Leg During Free Walking in Cockroaches [PDF]
, 1988 Fred Delcomyn
openalex +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Rhythmic and Bilaterally Coordinated Motor Activity in the Isolated Brain of Pleurobranchaea [PDF]
, 1984 Jill A. London, Rhanor Gillette
openalex +1 more source
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Molecular Oncology, EarlyView.Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki +2 more
wiley +1 more source