Results 71 to 80 of about 32,079 (217)
BacAv, a new free online platform for clinical back-averaging
Objective: The back-average technique is very useful to study the relation between the activity in the cortex and the muscles. It has two main clinical applications, Bereitschaftspotential (BP) recording and myoclonus studies.
Felipe Vial +3 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Linear switched system modelling and analysis for the servo system
Aiming at resolving the parameter uncertainty of the servo system under multi‐working conditions, a flatness‐based switched linear system model is proposed.
Qian Zhang +4 more
doaj +1 more source
Introduction: Small fiber polyneuropathy (SFP) is a common heralding clinical manifestation of damage to the nervous system in patients with familial amyloidosis.
Mar Guasp +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Whisking control by motor cortex
The rodent whiskers (the so-called vibrissae) are an active scanning sensorimotor system with major perceptual functions. Apart from tactile perception, the whisker motor system also has important contributions to the animals’ navigation and orientation capabilities.
Cornelius Schwarz +1 more
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
EFFECTS OF WALKING-INDUCED FATIGUE ON POSTURAL BALANCE AND RISK OF FALLS IN YOUNG AND OLDER PEOPLE
Pablo Arias +7 more
doaj +1 more source

