Results 1 to 10 of about 312,393 (166)
Motor neurons and the generation of spinal motor neurons diversity [PDF]
Frontiers in Cellular Neuroscience, 2014 Motor neurons (MNs) are neuronal cells located in the central nervous system (CNS) controlling a variety of downstream targets. This function infers the existence of MN subtypes matching the identity of the targets they innervate.
Nicolas eStifani
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Cardiac vagal motor neurons. [PDF]
Curr Opin NeurobiolSince their discovery five decades ago, cardiac vagal motor neurons (CVNs) have been studied for their roles in autonomic control of cardiac function. However, it is only within the past decade that our understanding of CVNs has rapidly progressed. Driven by technological advances in neuroscience, novel findings are revealing genetic markers of CVN's ...
Wang YB +3 more
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Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases. [PDF]
PLoS Genetics, 2017 The term "motor neuron disease" encompasses a spectrum of disorders in which motor neurons are the primary pathological target. However, in both patients and animal models of these diseases, not all motor neurons are equally vulnerable, in that while ...
Rachel A Kline +8 more
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Translatomic analysis of regenerating and degenerating spinal motor neurons in injury and ALS
iScience, 2021 Summary: The neuromuscular junction is a synapse critical for muscle strength and coordinated motor function. Unlike CNS injuries, motor neurons mount robust regenerative responses after peripheral nerve injuries.
Jennifer L. Shadrach +6 more
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Motor cortex analogue neurons in songbirds utilize Kv3 channels to generate ultranarrow spikes
eLife, 2023 Complex motor skills in vertebrates require specialized upper motor neurons with precise action potential (AP) firing. To examine how diverse populations of upper motor neurons subserve distinct functions and the specific repertoire of ion channels ...
Benjamin M Zemel +7 more
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Motor neurons in the escape response circuit of white shrimp (Litopenaeus setiferus) [PDF]
PeerJ, 2015 Many decapod crustaceans perform escape tailflips with a neural circuit involving giant interneurons, a specialized fast flexor motor giant (MoG) neuron, populations of larger, less specialized fast flexor motor neurons, and fast extensor motor neurons ...
Zen Faulkes
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A size principle for recruitment of Drosophila leg motor neurons
eLife, 2020 To move the body, the brain must precisely coordinate patterns of activity among diverse populations of motor neurons. Here, we use in vivo calcium imaging, electrophysiology, and behavior to understand how genetically-identified motor neurons control ...
Anthony W Azevedo +5 more
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Molecular Therapy: Methods & Clinical Development, 2020 The motor system controls muscle movement through lower motor neurons in the spinal cord and brainstem. Lower motor neurons are efferent neurons in the central nervous system (CNS) characterized by axonal projections that reach specific targets in the ...
Zhilong Chen +4 more
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Calcium imaging of CPG-evoked activity in efferent neurons of the stick insect. [PDF]
PLoS ONE, 2018 The stick insect is a well-established experimental animal to study the neural basis of walking. Here, we introduce a preparation that allows combining calcium imaging in efferent neurons with electrophysiological recordings of motor neuron activity in ...
Jens Goldammer +3 more
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Cell Reports, 2023 Summary: Motor neuron degeneration, the defining feature of amyotrophic lateral sclerosis (ALS), is a primary example of cell-type specificity in neurodegenerative diseases.
Aaron Held +10 more
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