Results 101 to 110 of about 2,308,037 (392)

Spatio-Temporal Patterning in Primary Motor Cortex at Movement Onset [PDF]

open access: yes, 2017
Voluntary movement initiation involves the engagement of large populations of motor cortical neurons around movement onset. Despite knowledge of the temporal dynamics that lead to movement, the spatial structure of these dynamics across the cortical ...
Best, Matthew D.   +4 more
core   +1 more source

Laminar dynamics of beta bursts in human motor cortex [PDF]

open access: green, 2021
James Bonaiuto   +5 more
openalex   +1 more source

Motor and emotional behaviours elicited by electrical stimulation of the human cingulate cortex

open access: yesBrain : a journal of neurology, 2018
The cingulate cortex is a mosaic of different anatomical fields, whose functional characterization is still a matter of debate. In humans, one method that may provide useful insights on the role of the different cingulate regions, and to tackle the issue
F. Caruana   +10 more
semanticscholar   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam   +6 more
wiley   +1 more source

Plasticity in One Hemisphere, Control From Two: Adaptation in Descending Motor Pathways After Unilateral Corticospinal Injury in Neonatal Rats

open access: yesFrontiers in Neural Circuits, 2018
After injury to the corticospinal tract (CST) in early development there is large-scale adaptation of descending motor pathways. Some studies suggest the uninjured hemisphere controls the impaired forelimb, while others suggest that the injured ...
Tong-Chun Wen   +11 more
doaj   +1 more source

Temporal Evolution of Both Premotor and Motor Cortical Tuning Properties Reflect Changes in Limb Biomechanics [PDF]

open access: yes, 2015
A prevailing theory in the cortical control of limb movement posits that premotor cortex initiates a high-level motor plan that is transformed by the primary motor cortex (MI) into a low-level motor command to be executed.
Hatsopoulos, Nicholas G.   +3 more
core   +2 more sources

Bypassing use-dependent plasticity in the primary motor cortex to preserve adaptive behavior [PDF]

open access: gold, 2021
Marion Bosc   +3 more
openalex   +1 more source

On the relations between the direction of two-dimensional arm movements and cell discharge in primate motor cortex

open access: yesJournal of Neuroscience, 1982
The activity of single cells in the motor cortex was recorded while monkeys made arm movements in eight directions (at 45 degrees intervals) in a two-dimensional apparatus. These movements started from the same point and were of the same amplitude.
Apostolos P. Georgopoul   +3 more
semanticscholar   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez   +12 more
wiley   +1 more source

Subtype-specific plasticity of inhibitory circuits in motor cortex during motor learning

open access: yesNature Neuroscience, 2015
Motor skill learning induces long-lasting reorganization of dendritic spines, principal sites of excitatory synapses, in the motor cortex. However, mechanisms that regulate these excitatory synaptic changes remain poorly understood.
Simon X. Chen   +3 more
semanticscholar   +1 more source

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