Results 101 to 110 of about 2,288,094 (289)

Neuropathic pain: transcranial electric motor cortex stimulation using high frequency random noise. Case report of a novel treatment

Journal of Pain Research, 2013
Per A Alm, Karolina DreimanisDepartment of Neuroscience, Uppsala University, Uppsala, SwedenObjectives: Electric motor cortex stimulation has been reported to be effective for many cases of neuropathic pain, in the form of epidural stimulation or ...
Alm PA, Dreimanis K
doaj  

Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology.

PLoS ONE, 2012
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance imaging (MRI) studies have previously shown hypointense signal in the motor cortex ...
Justin Y Kwan, Suh Young Jeong, Peter Van Gelderen, Han-Xiang Deng, Martha M Quezado, Laura E Danielian, John A Butman, Lingye Chen, Elham Bayat, James Russell, Teepu Siddique, Jeff H Duyn, Tracey A Rouault, Mary Kay Floeter   +13 more
doaj   +1 more source

Dissociating motor cortex from the motor

The Journal of Physiology, 2011
Abstract  During closed‐loop control of a brain–computer interface, neurons in the primary motor cortex can be intensely active even though the subject may be making no detectable movement or muscle contraction. How can neural activity in the primary motor cortex become dissociated from the movements and muscles of the native limb that it normally ...
openaire   +4 more sources

On the relations between the direction of two-dimensional arm movements and cell discharge in primate motor cortex

Journal of Neuroscience, 1982
The activity of single cells in the motor cortex was recorded while monkeys made arm movements in eight directions (at 45 degrees intervals) in a two-dimensional apparatus. These movements started from the same point and were of the same amplitude.
Apostolos P. Georgopoul, J. Kalaska, R. Caminiti, J. T. Massey   +3 more
semanticscholar   +1 more source

Temporal Evolution of Both Premotor and Motor Cortical Tuning Properties Reflect Changes in Limb Biomechanics [PDF]

, 2015
A prevailing theory in the cortical control of limb movement posits that premotor cortex initiates a high-level motor plan that is transformed by the primary motor cortex (MI) into a low-level motor command to be executed.
Hatsopoulos, Nicholas G., Lillicrap, Timothy P., Mardoum, Philip, Suminski, Aaron J.   +3 more
core   +2 more sources

Distinct Corticostriatal GABAergic Neurons Modulate Striatal Output Neurons and Motor Activity

Cell Reports, 2017
Summary: The motor cortico-basal ganglion loop is critical for motor planning, execution, and learning. Balanced excitation and inhibition in this loop is crucial for proper motor output.
Sarah Melzer, Mariana Gil, David E. Koser, Magdalena Michael, Kee Wui Huang, Hannah Monyer   +5 more
doaj   +1 more source

Plasticity in One Hemisphere, Control From Two: Adaptation in Descending Motor Pathways After Unilateral Corticospinal Injury in Neonatal Rats

Frontiers in Neural Circuits, 2018
After injury to the corticospinal tract (CST) in early development there is large-scale adaptation of descending motor pathways. Some studies suggest the uninjured hemisphere controls the impaired forelimb, while others suggest that the injured ...
Tong-Chun Wen, Sophia Lall, Corey Pagnotta, James Markward, Disha Gupta, Shivakeshavan Ratnadurai-Giridharan, Jacqueline Bucci, Lucy Greenwald, Madelyn Klugman, N. Jeremy Hill, Jason B. Carmel, Jason B. Carmel   +11 more
doaj   +1 more source

Robust neuronal dynamics in premotor cortex during motor planning

Nature, 2016
Neural activity maintains representations that bridge past and future events, often over many seconds. Network models can produce persistent and ramping activity, but the positive feedback that is critical for these slow dynamics can cause sensitivity to
Nuo Li, Kayvon Daie, K. Svoboda, S. Druckmann   +3 more
semanticscholar   +1 more source

Spatio-Temporal Patterning in Primary Motor Cortex at Movement Onset [PDF]

, 2017
Voluntary movement initiation involves the engagement of large populations of motor cortical neurons around movement onset. Despite knowledge of the temporal dynamics that lead to movement, the spatial structure of these dynamics across the cortical ...
Best, Matthew D., Brown, Kevin A., Hatsopoulos, Nicholas G., Suminski, Aaron J., Takahashi, Kazutaka   +4 more
core   +1 more source

Dynamic Re-wiring of Neural Circuits in the Motor Cortex in Mouse Models of Parkinson's Disease

Nature Neuroscience, 2015
Dynamic adaptations in synaptic plasticity are critical for learning new motor skills and maintaining memory throughout life, which rapidly decline with Parkinson's disease (PD). Plasticity in the motor cortex is important for acquisition and maintenance
Lili Guo, H. Xiong, Jae-Ick Kim, Yu-Wei Wu, Rupa R. Lalchandani, Yuting Cui, Y. Shu, T. Xu, Jun B. Ding   +8 more
semanticscholar   +1 more source