Results 81 to 90 of about 571,293 (344)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
Hand Motor Cortex Excitability During Speaking in Persistent Developmental Stuttering
Frontiers in Human Neuroscience, 2019 Persistent developmental stuttering (PDS) is a speech fluency disorder characterized by intermittent involuntary breakdowns of speech motor control, possibly related to motor cortex excitability.
Martin Sommer +3 more
doaj +1 more source
Protein Synthesis Inhibition in the Peri-Infarct Cortex Slows Motor Recovery in Rats. [PDF]
PLoS ONE, 2016 Neuroplasticity and reorganization of brain motor networks are thought to enable recovery of motor function after ischemic stroke. Especially in the cortex surrounding the ischemic scar (i.e., peri-infarct cortex), evidence for lasting reorganization has
Maximilian Schubring-Giese +3 more
doaj +1 more source
Spatio-Temporal Patterning in Primary Motor Cortex at Movement Onset [PDF]
, 2017 Voluntary movement initiation involves the engagement of large populations of motor cortical neurons around movement onset. Despite knowledge of the temporal dynamics that lead to movement, the spatial structure of these dynamics across the cortical ...
Best, Matthew D. +4 more
core +1 more source
Sensing with the Motor Cortex [PDF]
Neuron, 2011 The primary motor cortex is a critical node in the network of brain regions responsible for voluntary motor behavior. It has been less appreciated, however, that the motor cortex exhibits sensory responses in a variety of modalities including vision and somatosensation.
Hatsopoulos, Nicholas G. +1 more
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin +12 more
wiley +1 more source
PLoS ONE, 2012 Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance imaging (MRI) studies have previously shown hypointense signal in the motor cortex ...
Justin Y Kwan +13 more
doaj +1 more source
Dissociating motor cortex from the motor
The Journal of Physiology, 2011 Abstract During closed‐loop control of a brain–computer interface, neurons in the primary motor cortex can be intensely active even though the subject may be making no detectable movement or muscle contraction. How can neural activity in the primary motor cortex become dissociated from the movements and muscles of the native limb that it normally ...
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source
Distinct Corticostriatal GABAergic Neurons Modulate Striatal Output Neurons and Motor Activity
Cell Reports, 2017 Summary: The motor cortico-basal ganglion loop is critical for motor planning, execution, and learning. Balanced excitation and inhibition in this loop is crucial for proper motor output.
Sarah Melzer +5 more
doaj +1 more source