Results 61 to 70 of about 1,651,137 (254)

Task-free functional MRI in cervical dystonia reveals multi-network changes that partially normalize with botulinum toxin. [PDF]

open access: yesPLoS ONE, 2013
Cervical dystonia is characterized by involuntary, abnormal movements and postures of the head and neck. Current views on its pathophysiology, such as faulty sensorimotor integration and impaired motor planning, are largely based on studies of focal hand
Cathérine C S Delnooz   +3 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Cell type specific connections from primary motor to primary somatosensory cortex. [PDF]

open access: yes, 2013
Anatomical studies have shown that primary somatosensory (S1) and primary motor (M1) cortices are reciprocally connected. The pathway from primary motor cortex (M1) to primary somatosensory cortex (S1) is thought to influence activity in S1 by ...
Kinnischtzke, Amanda K
core  

Induction of plasticity in the human motor cortex by pairing an auditory stimulus with TMS

open access: yesFrontiers in Human Neuroscience, 2014
Acoustic stimuli can cause a transient increase in the excitability of the motor cortex. The current study leverages this phenomenon to develop a method for testing the integrity of auditorimotor integration and the capacity for auditorimotor plasticity.
Paul Fredrick Sowman   +7 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Effect of electroacupuncture stimulation of “Sibai”(ST2) and “Quanliao”(SI18) on excitatory neurons of sensorimotor cortex in mice

open access: yes针刺研究
ObjectiveTo observe the activation state and neuronal types of somatosensory cortex and the primary motor cortex induced by electroacupuncture (EA) stimulation of “Sibai” (ST2) and “Quanliao” (SI18) acupoints in mice.MethodsMale C57BL/6J mice were ...
ZHANG Zhi-qing   +8 more
doaj   +2 more sources

Hand Motor Cortex Excitability During Speaking in Persistent Developmental Stuttering

open access: yesFrontiers in Human Neuroscience, 2019
Persistent developmental stuttering (PDS) is a speech fluency disorder characterized by intermittent involuntary breakdowns of speech motor control, possibly related to motor cortex excitability.
Martin Sommer   +3 more
doaj   +1 more source

Protein Synthesis Inhibition in the Peri-Infarct Cortex Slows Motor Recovery in Rats. [PDF]

open access: yesPLoS ONE, 2016
Neuroplasticity and reorganization of brain motor networks are thought to enable recovery of motor function after ischemic stroke. Especially in the cortex surrounding the ischemic scar (i.e., peri-infarct cortex), evidence for lasting reorganization has
Maximilian Schubring-Giese   +3 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec   +6 more
wiley   +1 more source

Signals from posterior parietal area 5 to motor cortex during locomotion

open access: yes, 2022
Area 5 of the parietal cortex is part of the "dorsal stream" cortical pathway which processes visual information for action. The signals that area 5 ultimately conveys to motor cortex, the main area providing output to the spinal cord, are unknown.
Di Prisco, Gonzalo Viana   +10 more
core   +1 more source

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