Results 41 to 50 of about 1,651,137 (254)

Influence of stimulant medication and response speed on lateralization of movement-related potentials in attention-deficit/hyperactivity disorder. [PDF]

, 2012
Hyperactivity is one of the core symptoms in attention deficit hyperactivity disorder (ADHD). However, it remains unclear in which way the motor system itself and its development are affected by the disorder.
Resch, Franz, Stephan Bender, Matthias Weisbrod, Fallgatter Andreas J., Romanos Marcel, Klein Christoph, Marcel Romanos, Romanos, Marcel, Klein, Christoph, Andreas J. Fallgatter, Christoph Klein, Fallgatter, Andreas J., Franz Resch (157990), Bender, Stephan, Weisbrod, Matthias, Christoph Klein (157998), Renner Tobias, Weisbrod Matthias, Marcel Romanos (74361), Renner, Tobias, Tobias Renner (158008), Tobias Renner, Andreas J. Fallgatter (158018), Bender Stephan, Franz Resch, Andreas J Fallgatter, Resch Franz, Stephan Bender (157984), Matthias Weisbrod (158023)   +28 more
core   +2 more sources

Role of the motor cortex in the generation of classically conditioned eyelid and vibrissae responses

Scientific Reports, 2021
The eyelid motor system has been used for years as an experimental model for studying the neuronal mechanisms underlying motor and cognitive learning, mainly with classical conditioning procedures. Nonetheless, it is not known yet which brain structures,
Juan C. López-Ramos, José M. Delgado-García   +1 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

A systematic review of high-frequency transcranial magnetic stimulation on motor cortex areas as a migraine preventive treatment

Cephalalgia Reports, 2019
Background: The results of high-frequency repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex for migraine have been inconsistent.
Ryan Hulla, Angela Liegey-Dougall
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Investigation of the interaction between corticomuscular coherence, motor precision and perceived difficulty in wrist flexion and extension [PDF]

, 2013
Includes abstract.Includes bibliographical references.Recently, behavioural (motor precision) differences were reported between isometric wrist flexion and extension.
Divekar, Nikhil Vishwas
core   +1 more source

Differences in high-definition transcranial direct current stimulation over the motor hotspot versus the premotor cortex on motor network excitability

Scientific Reports, 2019
The effectiveness of transcranial direct current stimulation (tDCS) placed over the motor hotspot (thought to represent the primary motor cortex (M1)) to modulate motor network excitability is highly variable.
Stephanie Lefebvre, Kay Jann, Allie Schmiesing, Kaori Ito, Mayank Jog, Nicolas Schweighofer, Danny J. J. Wang, Sook-Lei Liew   +7 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source