Results 41 to 50 of about 561,492 (257)

State Variables of the Arm May Be Encoded by Single Neuron Activity in the Monkey Motor Cortex [PDF]

open access: yes, 2016
Revealing the type of information encoded by neurons activity in the motor cortex is essential not only for understanding the mechanism of motion control but also for developing a brain-machine interface.
Eizo Miyashita, Yutaka Sakaguchi
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A systematic review of high-frequency transcranial magnetic stimulation on motor cortex areas as a migraine preventive treatment

open access: yesCephalalgia Reports, 2019
Background: The results of high-frequency repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex for migraine have been inconsistent.
Ryan Hulla, Angela Liegey-Dougall
doaj   +1 more source

Connections of the Mesencephalic Locomotor Region (MLR) in the Cat [PDF]

open access: yes, 1980
The cat entopeduncular nucleus (EN), which is the main output of the basal ganglia, is known to project to the mesencephalic tegmentum. We have been able to elicit antidromic responses in single EN neurons from the region of the mesencephalic locomotor ...
Garcia-Rill, E.   +2 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Differences in high-definition transcranial direct current stimulation over the motor hotspot versus the premotor cortex on motor network excitability

open access: yesScientific Reports, 2019
The effectiveness of transcranial direct current stimulation (tDCS) placed over the motor hotspot (thought to represent the primary motor cortex (M1)) to modulate motor network excitability is highly variable.
Stephanie Lefebvre   +7 more
doaj   +1 more source

Multimodal Representation of Space in the Posterior Parietal Cortex and its use in Planning Movements [PDF]

open access: yes, 1997
Recent experiments are reviewed that indicate that sensory signals from many modalities, as well as efference copy signals from motor structures, converge in the posterior parietal cortex in order to code the spatial locations of goals for movement ...
Andersen, Richard A.   +3 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Motor Cortex Stimulation for pain relief : do corollary discharges play a role? [PDF]

open access: yes, 2016
Both invasive and non-invasive motor cortex stimulation techniques have been successfully employed in the treatment of chronic pain, but the precise mechanism of action of such treatments is not fully understood.
Brasil Neto, Joaquim Pereira
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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