Results 41 to 50 of about 1,595,332 (298)
Unmasking of latent synaptic connections in the cortex of the rat, elicited by a facial nerve transection [PDF]
Peripheral nerve injury elicits plastic changes in the cortex, resulting in reorganization of the somatotopic representation maps. These processes begin within minutes after nerve injury, and last for weeks.
Toldi, József +3 more
core +1 more source
Modified constraint-induced movement therapy (mCIMT) has shown beneficial effects on motor function improvement after brain injury, but the exact mechanism remains unclear.
Cheng-Cheng Sun +12 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Patterns of myeloarchitecture in lower limb amputees: an MRI study
Functional studies of cortical plasticity in humans suggest that the motor cortex reorganizes when the descending motor output pathway is disrupted as a result of limb amputation.
Eyesha eHashim +3 more
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Baby steps: investigating the development of perceptual-motor couplings in infancy [PDF]
There are cells in our motor cortex that fire both when we perform and when we observe similar actions. It has been suggested that these perceptual-motor couplings in the brain develop through associative learning during correlated sensorimotor ...
Carina C.J.M. de Klerk +10 more
core +1 more source
Background: The results of high-frequency repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex for migraine have been inconsistent.
Ryan Hulla, Angela Liegey-Dougall
doaj +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
The effectiveness of transcranial direct current stimulation (tDCS) placed over the motor hotspot (thought to represent the primary motor cortex (M1)) to modulate motor network excitability is highly variable.
Stephanie Lefebvre +7 more
doaj +1 more source
Role of the motor cortex in the generation of classically conditioned eyelid and vibrissae responses
The eyelid motor system has been used for years as an experimental model for studying the neuronal mechanisms underlying motor and cognitive learning, mainly with classical conditioning procedures. Nonetheless, it is not known yet which brain structures,
Juan C. López-Ramos +1 more
doaj +1 more source

