Results 91 to 100 of about 2,267,071 (351)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Spinal and Supraspinal Motor Control Predictors of Rate of Torque Development [PDF]

, 2015
During explosive movements and potentially injurious situations, the ability to rapidly generate torque is critical. Previous research has suggested that different phases of rate of torque development (RTD) are differentiately controlled.
Hoffman, M. A., Johnson, S. T., Kipp, Kristof, Norcross, m. F.   +3 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Iron Deficiency in Infancy and Its Impact on Motor and Mental Development [PDF]

, 2020
Iron plays a large role in nerve myelination, dopamine neurotransmission, and neuronal metabolism. The purpose of this literary review was to investigate the connection between iron deficiency and motor and cognitive development.
Baker, Emma
core   +1 more source

Triple-Layer Porous Transport Layers with Ultra-High Porosity for Enhanced Oxygen Transport and Catalyst Utilization in Water Electrolysis

Nano-Micro Letters
Highlights A novel triple-layer Ti-porous transport layer (PTL), fabricated using a practical and scalable tape casting and roll calendering process, enhances catalyst utilization by increasing interfacial contact area and the triple-phase boundary.
Seong Hyun Park, Young Je Park, Seungsoo Jang, Pilyoung Lee, Soobin Yoon, Young-June Park, Chi-Young Jung, Kang Taek Lee   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Development and Implementation - DSIF Development [PDF]

Antenna system instrumentation, phase modulator designs, control systems for transmitter and motor generator, and related DSIF ...

core   +1 more source

Description of Motor Skill Development and Parent Socio-Economic Status of West Java Little League Baseball Athletes [PDF]

, 2021
Gano Sumarno, Andi Suntoda Situmorang, Mesa Rahmi Stephani, Ricky Wibowo   +3 more
openalex   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A microscopic model for chemically-powered Janus motors

, 2016
Very small synthetic motors that make use of chemical reactions to propel themselves in solution hold promise for new applications in the development of new materials, science and medicine. The prospect of such potential applications, along with the fact
Huang, Mu-Jie, Kapral, Raymond, Schofield, Jeremy   +2 more
core   +1 more source