Results 191 to 200 of about 630,149 (257)

Examining associations between human milk fatty acids, oligosaccharides, and early infant cognitive, language and motor development in the CHILD cohort study. [PDF]

Front Nutr
Turner SE, Roos LE, Nickel NC, Moraes TJ, Turvey SE, Simons E, Subbarao P, Robertson B, Chikuma J, Goruk S, Field CJ, Bode L, Pei J, Mandhane PJ, Azad MB.   +14 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Relationship Between the Use of Screens and the Motor Development of Children from 8 to 10 Years of Age. [PDF]

Children (Basel)
Páez-Herrera J, Álvarez-González S, López-Lara S, Otero-Tricio C, Rojas-Martínez W, Salgado-Díaz S, Yáñez-Sepúlveda R, Hurtado-Almonacid J.   +7 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The needs of parents and their network to influence physical activity and motor development among children 0-to-4-years old: a mixed-methods study protocol. [PDF]

BMC Public Health
Wagijo MR, Altenburg TM, Ledebt A, Bartels F, van der Kaap RK, Bel K, Voorwinden S, van Doodewaard C, van Kann DHH, Gubbels JS, de Moor MHM, ASAS-consortium.   +11 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Small for Gestational Age and Motor Development in Children: A Narrative Review of Risk Factors, Brain Mechanisms, and Early Interventions.

Dev Neurosci
Zhu L, Yao D.
europepmc   +1 more source

Sex Differences in the Striatal Contributions to Longitudinal Fine Motor Development in Autistic Children. [PDF]

Biol Psychiatry
Surgent O, Andrews DS, Lee JK, Boyle J, Dakopolos A, Miller M, Ozonoff S, Rogers SJ, Solomon M, Amaral DG, Nordahl CW.   +10 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Parent-Reported Relations Between Vocabulary and Motor Development in Infancy: Differences Between Verbs and Nouns. [PDF]

Infancy
Frewin KL, Gerson SA, Vanderwert RE, Gambi C.   +3 more
europepmc   +1 more source