Results 91 to 100 of about 147,703 (303)

Raising sector skills levels : how responsive is local training supply? [PDF]

open access: yes, 2005
This UK study examines the extent and nature of any mismatches between the training requirements of employers and the local provision of vocational education and training (VET).
Mason, Geoff   +2 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

ANALYSIS OF INDUCTION MOTOR WITH BROKEN BARS AND CONSTANT SPEED USING CIRCUIT-FIELD COUPLED METHOD

open access: yesJournal of Fundamental and Applied Sciences, 2015
The paper presents the use of the two-dimensional finite element method for modeling the three-phase squirrel-cage induction motor by using circuit coupled method. In order to analyze the machine performances, the voltage source is considered.
N. Halem, S. E. Zouzou, K. Srairi
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Fault Diagnostics of Synchronous Motor Based on Artificial Intelligence

open access: yesMachines
Electrical motors and drives are the unseen forces driving our modern world, powering everything from electric vehicles to industrial machinery. The efficiency, precision, and sustainability of these systems are very important.
Samir Abood   +3 more
doaj   +1 more source

Neonatal Diagnostics: Towards Dynamic Growth Charts of Neuro-motor control

open access: yesFrontiers in Pediatrics, 2016
Current rise of neurodevelopmental disorders, poses a critical need to detect risk early in order to rapidly intervene. One of the tools Pediatricians use to track development is the standard Growth Chart.
Elizabeth B Torres   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

CHANGES OF GASTRiC AND ESOPHAGEAL MOTOR ACTiViTY AT SOME PATHOLOGiCAL CONDiTiONS OF STOMACH

open access: yesActa Biomedica Scientifica, 2012
The article reviews problem, of changes of gastric and esophageal motor activity at the pathologies of gastrointestinal tract. Obtained data allow to estimate value of gastric motor activity in the pathogenesis of such diseases as chronic gastritis ...
A. V. Tobokhov   +2 more
doaj  

Diagnostic value of neurophysiological complex “transcranial magnetic stimulation – electroneuromyography” at spondilogenic cervical myelopathy

open access: yesUkrainian Neurosurgical Journal, 2011
Movement disorders diagnostics in patients with spondilogenic cervical myelopathy (SCV) was improved using complex of transcranial magnetic stimulation (TMS) and electroneuromyography (ENMG).Neurophysiological (NPh) research of segmental and ...
Albina Tretiakova, Lidiya Chebotariova
doaj   +1 more source

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