Results 61 to 70 of about 46,876 (266)
The Main Directions in Development of Machine Transmission Unit Diagnostics
Механика машин, механизмов и материалов, 2014 The state of vibration diagnostics of technical objects, peculiarities of hardware and software of manufacturers’ products, approaches and methods for diagnostics of mobile machines transmission systems are considered. The systems of mobile machines gear
N.N. Ishin , V.B. Algin
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
ANALYSIS OF INDUCTION MOTOR WITH BROKEN BARS AND CONSTANT SPEED USING CIRCUIT-FIELD COUPLED METHOD
Journal of Fundamental and Applied Sciences, 2015 The paper presents the use of the two-dimensional finite element method for modeling the three-phase squirrel-cage induction motor by using circuit coupled method. In order to analyze the machine performances, the voltage source is considered.
N. Halem, S. E. Zouzou, K. Srairi
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Fault Diagnostics of Synchronous Motor Based on Artificial Intelligence
MachinesElectrical motors and drives are the unseen forces driving our modern world, powering everything from electric vehicles to industrial machinery. The efficiency, precision, and sustainability of these systems are very important.
Samir Abood +3 more
doaj +1 more source
Ukrainian Neurosurgical Journal, 2011 Movement disorders diagnostics in patients with spondilogenic cervical myelopathy (SCV) was improved using complex of transcranial magnetic stimulation (TMS) and electroneuromyography (ENMG).Neurophysiological (NPh) research of segmental and ...
Albina Tretiakova, Lidiya Chebotariova
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
CHANGES OF GASTRiC AND ESOPHAGEAL MOTOR ACTiViTY AT SOME PATHOLOGiCAL CONDiTiONS OF STOMACH
Acta Biomedica Scientifica, 2012 The article reviews problem, of changes of gastric and esophageal motor activity at the pathologies of gastrointestinal tract. Obtained data allow to estimate value of gastric motor activity in the pathogenesis of such diseases as chronic gastritis ...
A. V. Tobokhov +2 more
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