Results 101 to 110 of about 1,837,959 (291)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
History of the Ohio Bureau of Motor Vehicles
, 2001 Title from caption (viewed Mar.
Ohio. Bureau of Motor Vehicles.
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A High-Performance and Cost-Effective Field Programmable Gate Array-Based Motor Drive Emulator. [PDF]
Micromachines (Basel), 2023 Hernandez J +2 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Feasibility of high-frequency alternating current power for motor auxiliary loads in vehicles
, 2011 This paper presents a feasibility study into the application of a 100-V, 50-kHz high-frequency ac (HFAC) network for powering automotive electrical auxiliaries. The study is focused on motor-actuated loads and is divided into two sections.
Nicholas D. Vaughan +5 more
core +1 more source
Features of using low-pass filter for small signal demodulation in phase-locking motor drive
Омский научный вестникPhase-locking motor drive based on phase-lock principal provides high accuracy and wide shaft speed range. А low-pass filter is used for PWM-signal demodulation in phase-lock loop. This type of demodulator limits loop bandwidth and working range of motor
A. V. Bubnov, A. M. Daynovich
doaj +1 more source
Sensor Fault Diagnosis Method Based on Rotor Slip Applied to Induction Motor Drive. [PDF]
Sensors (Basel), 2022 Tran CD +4 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source