Results 141 to 150 of about 884,436 (268)

Characterization and snubbing of a bidirectional MCT in a resonant ac link converter [PDF]

open access: yes
The MOS-Controlled Thyristor (MCT) is emerging as a powerful switch that combines the better characteristics of existing power devices. A study of switching stresses on an MCT switch under zero voltage resonant switching is presented.
Elbuluk, Malik E.   +2 more
core   +1 more source

Vertical axis wind turbine drive train transient dynamics [PDF]

open access: yes, 1982
Start up of a vertical axis wind turbine causes transient torque oscillations in the drive train with peak torques which may be over two and one half times the rated torque of the turbine.
Carne, T. G., Clauss, D. B.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Research on trajectory tracking control method for agricultural robot permanent magnet synchronous motor servo system based on improved EMD threshold wavelet filtering

open access: yesAIP Advances
In agricultural robots, trajectory tracking can be affected by disturbances such as road slopes or bumps, leading to sudden changes in path curvature and reduced control accuracy. To address this issue, we propose a servo motor drive control method based
Bo Shen   +3 more
doaj   +1 more source

The effects of gear reduction on robot dynamics [PDF]

open access: yes
The effect of the joint drive system with gear reduction for a generic two-link system is studied. It is done by comparing the kinetic energy of such a system with that of a direct drive two-link system.
Chen, J.
core   +1 more source

Simulation of speed control brushless DC motor using gaussian fuzzy logic controller [PDF]

open access: yes, 2014
This paper presents a control scheme of a Fuzzy Logic for the brushless direct current (BLDC) motor drives. The BLDC motor has some advantages compare to others type of motors.
Abd Karim, Nurliana
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Design optimization of a slotless PM brushless motor with spiral wound laminations for rim driven thrusters

open access: yes, 2009
This paper discusses the analysis and design of a very thin slotless PM brushless motor whose stator laminations are manufactured from a single strip of steel that is edge wound into a spiral (like a “Slinky”) and then fitted over the windings that are ...
Lai, S.H., Sharkh, S.M.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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