Results 81 to 90 of about 214,794 (300)

Voluntary activation of human knee extensors measured using transcranial magnetic stimulation [PDF]

open access: yes, 2009
The aim of this study was to determine the applicability and reliability of a transcranial magnetic stimulation twitch interpolation technique for measuring voluntary activation of a lower limb muscle group.
Goodall, Stuart, Romer, Lee, Ross, Emma
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]

open access: yes, 2015
Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine   +2 more
core   +2 more sources

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Predictive modeling of TMS-evoked responses: Unraveling instantaneous excitability states

open access: yesNeuroImage
Transcranial magnetic stimulation (TMS) combined with electroencephalography (EEG) and electromyography (EMG) provides a unique window into instantaneous cortical and corticospinal excitability states. We investigated 50 healthy participants to determine
Oskari Ahola   +12 more
doaj   +1 more source

Brain Activity Underlying Muscle Relaxation

open access: yesFrontiers in Physiology, 2019
Fine motor control of not only muscle contraction but also muscle relaxation is required for appropriate movements in both daily life and sports. Movement disorders such as Parkinson’s disease and dystonia are often characterized by deficits of muscle ...
Kouki Kato   +3 more
doaj   +1 more source

A Novel Latency Estimation Algorithm of Motor Evoked Potential Signals

open access: yesIEEE Access, 2020
Evaluation of motor evoked potential (MEP) signals elicited by transcranial magnetic stimulation (TMS) over the motor cortex provide a measure of cortico-motor excitability at the time of stimulation.
Josko Soda   +4 more
doaj   +1 more source

Bringing BCI into everyday life: Motor imagery in a pseudo realistic environment [PDF]

open access: yes, 2015
Bringing Brain-Computer Interfaces (BCIs) into everyday life is a challenge because an out-of-lab environment implies the presence of variables that are largely beyond control of the user and the software application.
Brandl, Stephanie   +3 more
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

The influence of chronic occupational exposure to lead on peripheral nerves conduction

open access: yesMedycyna Pracy
Background The impact of lead on the peripheral nervous system (PNS) remains inadequately explored. Despite the absence of classic lead neuropathy resulting from uncontrolled exposure to high metal doses in workers under biomonitoring, the focus shifts ...
Małgorzata Cisowska   +4 more
doaj   +1 more source

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