Results 91 to 100 of about 1,642,125 (295)
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Motor-evoked responses in primary lateral sclerosis.
Primary lateral sclerosis (PLS) may be distinguished on the basis of clinical and pathological features from amyotrophic lateral sclerosis (ALS). The former is featured by a much longer clinical course, exclusively upper motor neuron findings, losses of ...
A. J. Hudson +4 more
core +1 more source
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Examples of motor and somatosensory evoked potentials.
A) Example of a motor evoked potential (MEP); B) Example of a Somatosensory Evoked Potential (SSEP). (TIF)
Pablo Brea Winckler (11773044) +8 more
core +1 more source
Ketamine-Based Anesthetic Protocols and Evoked Potential Monitoring: A Risk/Benefit Overview
Since its discovery, ketamine, a noncompetitive N-methyl D-aspartate (NMDA) receptor antagonist related to phencyclidine, has been linked to multiple adverse reactions sometimes described as out of body and near death experiences, including emergence ...
Nicoleta eStoicea +8 more
doaj +1 more source
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
A. CxL in upper limbs; B, upper limb motor CCT; C, CxL in lower limbs; D, lower limb motor CCT; E, N20; F, upper limb sensory CCT; G, P40; H, lower limb sensory CCT. Black dots indicate patients with a relapse.
Ming-Fen Lao (665756) +10 more
core +1 more source
Background: Walking recovery is one of the main goals of patients after SCI. Walking is rated as primary goal and desire (together with bladder and bowel function) irrespective of the level of lesion. Past literature terms walking as long-term outcome or
Parneet Kaur Bedi , Narkeesh Arumugam
doaj +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Prognostic Values of Motor Evoked Potentials in Insular, Precental, or Postcentral Resections
To determine the predictive values of motor evoked potentials (MEPs) on the muscle strength of patients undergoing insular and/or around precentral or postcentral ...
Boex, Colette +7 more
core +1 more source

