Results 61 to 70 of about 61,982 (304)
International Journal of Physiotherapy, 2015 Background: Walking recovery is one of the main goals of patients after SCI. Walking is rated as primary goal and desire (together with bladder and bowel function) irrespective of the level of lesion. Past literature terms walking as long-term outcome or
Parneet Kaur Bedi , Narkeesh Arumugam
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DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
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Transcranial static magnetic field stimulation - new non-invasive brain stimulation tool
Journal of Physical Fitness and Sports Medicine, 2016 Recent research has shown that the human motor cortex can be modulated by the application of static magnetic fields through the scalp. Transcranial static magnetic field stimulation (tSMS) has since received significant attention as a new non-invasive ...
Hikari Kirimoto +2 more
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TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
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FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
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Magnetic Motor Evoked Potentials in Ponies
Journal of Veterinary Internal Medicine, 1996 Magnetic stimulation of motor pathways was used to effect motor unit action potential recordings from forelimb and hindlimb muscles in unanesthetized ponies. Motor pathway conduction velocities to the forelimb and hindlimb were determined to be 53.8 ± 9.6 m/s‐1and 63.4 ± 8.3 m/s‐1, respectively.
I G, Mayhew, J R, Washbourne
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FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
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Ketamine-Based Anesthetic Protocols and Evoked Potential Monitoring: A Risk/Benefit Overview
Frontiers in Neuroscience, 2016 Since its discovery, ketamine, a noncompetitive N-methyl D-aspartate (NMDA) receptor antagonist related to phencyclidine, has been linked to multiple adverse reactions sometimes described as out of body and near death experiences, including emergence ...
Nicoleta eStoicea +8 more
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Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
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