Results 211 to 220 of about 305,411 (311)

Structure-function association of the cerebellar motor network is altered in isolated cervical dystonia. [PDF]

J Neurol
Grimm K, Braaß H, Sadeghi F, Gelderblom M, Schulz R, Zittel S.   +5 more
europepmc   +1 more source

Transient, developmental functional and structural connectivity abnormalities in the thalamocortical motor network in Rolandic epilepsy. [PDF]

Neuroimage Clin, 2022
Kwon H, Chinappen DM, Huang JF, Berja ED, Walsh KG, Shi W, Kramer MA, Chu CJ.   +7 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Motor network pre-habilitation by low-frequency repetitive transcranial magnetic stimulation. A proof-of-concept. [PDF]

Acta Neurochir (Wien)
Ben Dor N, Raffa G, Scibilia A, Espahbodinea S, Garcia C, La Torre D, Ziv G, Friso F, Granata F, Vinci S, Rustici A, Cardali SM, Garufi G, Cirillo L, Giannini G, Martinoni M, Zoli M, Tonon C, Lodi R, Conti A.   +19 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Correction to: Motor network pre-habilitation by low-frequency repetitive transcranial magnetic stimulation. A proof-of-concept. [PDF]

Acta Neurochir (Wien)
Dor NB, Raffa G, Scibilia A, Espahbodinea S, Garcia C, La Torre D, Ziv G, Friso F, Granata F, Vinci S, Rustici A, Cardali SM, Garufi G, Cirillo L, Giannini G, Martinoni M, Zoli M, Tonon C, Lodi R, Conti A.   +19 more
europepmc   +1 more source

Cerebellar stimulation prevents Levodopa-induced dyskinesia in mice and normalizes activity in a motor network. [PDF]

Nat Commun, 2022
Coutant B, Frontera JL, Perrin E, Combes A, Tarpin T, Menardy F, Mailhes-Hamon C, Perez S, Degos B, Venance L, Léna C, Popa D.   +11 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Motor network reorganization associated with rTMS-induced writing improvement in writer's cramp dystonia. [PDF]

Brain Stimul
Bukhari-Parlakturk N, Mulcahey PJ, Lutz MW, Ghazi R, Huang Z, Dannhauer M, Termsarasab P, Scott B, Simsek ZB, Groves S, Lipp M, Fei M, Tran TK, Wood E, Beynel L, Petty C, Voyvodic JT, Appelbaum LG, Al-Khalidi HR, Davis SW, Michael AM, Peterchev AV, Calakos N.   +22 more
europepmc   +1 more source

Cerebello-thalamic activity drives an abnormal motor network into dystonic tremor. [PDF]

Neuroimage Clin, 2022
Nieuwhof F, Toni I, Dirkx MF, Gallea C, Vidailhet M, Buijink AWG, van Rootselaar AF, van de Warrenburg BPC, Helmich RC.   +8 more
europepmc   +1 more source