Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki+11 more
wiley +1 more source
EFFECT OF THE PROSTATIC EXTRACT (ROBAVERON) ON BLADDER FUNCTION : AN EXPERIMENTAL STUDY 3 -RESULT OF PHYSIOLOGICAL AND BIOCHEMICAL STUDY ON THE EXPERIMENTAL NEUROGENIC BLADDER - [PDF]
Through the physiological and the biochemical study, the effects of prostatic extract (Robaveron) were investigated on the rabbits with experimental motor neuron lesion by the perfect transsection of the spinal cord. Experiments were carried out with two
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core
Identification of pathways of degeneration and protection in motor neuron diseases [PDF]
Motor neuron diseases preferentially affect specific neuronal populations with distinct clinical features even if disease-causing genes are expressed in many cell types. In spinal muscular atrophy (SMA), somatic motor neurons are selectively vulnerable
Nichterwitz, Susanne
core +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Generation of reactive oxygen species (ROS) has been shown to be important for many physiological processes, ranging from cell differentiation to apoptosis. With the development of the genetically encoded photosensitiser KillerRed (KR) it is now possible
Isabel Formella+8 more
doaj
The Aging Neuromuscular System and Motor Performance [PDF]
Age-related changes in the basic functional unit of the neuromuscular system, the motor unit, and its neural inputs have a profound effect on motor function, especially among the expanding number of old (older than ∼60 yr) and very old (older than ∼80 yr)
Hunter, Sandra K.+2 more
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Specifiying Motor Neurons and their Connections [PDF]
The two papers described above provide important insights into two steps in the differentiation program of motor neurons. Motor neurons are the primary efferent class of neurons in the spinal cord and are an essential component of locomotor circuits in the spinal cord.
openaire +3 more sources
Matrix: a complex amalgam of structures and functions in tumor microenvironment
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis+3 more
wiley +1 more source
Penerapan Kontroler Neural Fuzzy Untuk Pengendalian Kecepatan Motor Induksi 3 Fasa Pada Mesin Sentrifugal [PDF]
Motor induksi 3 fasa adalah alat penggerak yang paling banyak digunakan dalam dunia industri. Salah satu aplikasi motor induksi pada industri gula adalah pada mesin sentrifugal yang digunakan pada proses sentrifugasi.
Fauziyah, M. (Mila)+2 more
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Effect of the Butyrate Prodrug Pivaloyloxymethyl Butyrate (AN9) on a Mouse Model for Spinal Muscular Atrophy. [PDF]
Spinal muscular atrophy (SMA) is an early-onset motor neuron disease that leads to loss of muscle function. Butyrate (BA)-based compounds markedly improve the survival and motor phenotype of SMA mice.
Butchbach, Matthew E.R.+1 more
core +2 more sources