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Autophagy in motor neuron diseases

2020
Motor neuron diseases (MNDs) are a wide group of neurodegenerative disorders characterized by the degeneration of a specific neuronal type located in the central nervous system, the motor neuron (MN). There are two main types of MNs, spinal and cortical MNs and depending on the type of MND, one or both types are affected.
openaire   +3 more sources

Astrocytes in Motor Neuron Diseases

2019
Motor neuron disorders are highly debilitating and mostly fatal conditions for which only limited therapeutic options are available. To overcome this limitation and develop more effective therapeutic strategies, it is critical to discover the pathogenic mechanisms that trigger and sustain motor neuron degeneration with the greatest accuracy and detail.
Valori, Chiara F.   +3 more
openaire   +3 more sources

Motor neuron disease

2018
Motor neuron disease (MND) is characterized by progressive muscular weakness due to simultaneous degeneration of lower and upper motor neurons (L/UMNs). Involvement of LMNs, arising from the anterior horns of the spinal cord and brainstem, leads to secondary wasting as a result of muscle denervation.
openaire   +1 more source

Trophic protection of motor neurons: clinical potential in motor neuron diseases

Journal of Neurology, 1994
Recent advances in understanding the physiologic role of nerve growth factor (NGF), obtained both from tissue culture and efficacy studies in animals, have suggested that neurotrophic factors may have clinical potential in the treatment of neurodegenerative diseases or nerve trauma [12,21].
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Motor neurone disease and the life of motor neurones

Medical Journal of Australia, 1997
Jacqueline A Bansal, Amolak S Bansal
openaire   +2 more sources

A Photoelectric Spiking Neuron for Visual Depth Perception

Advanced Materials, 2022
Yongli He, Yi Shi, Changjin Wan
exaly  

Motor Neurone Disease

Reviews in Clinical Gerontology, 1995
openaire   +2 more sources

Motor Neuron Disease

Neurologic Clinics, 2015
Richard J. Barohn, Mazen M. Dimachkie
openaire   +2 more sources

Development of Neuroregenerative Gene Therapy to Reverse Glial Scar Tissue Back to Neuron-Enriched Tissue

Frontiers in Cellular Neuroscience, 2020
Vishal Swaminathan, Gong Chen
exaly  

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