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The Use of Digital Devices to Monitor Physical Behavior in Motor Neuron Disease: Systematic Review.
J Med Internet ResMusson LS +17 more
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Neurons but Motor Neurons in Motor Neuron disease
Italian journal of anatomy and embryology, 2013The occurrence of motor neuron death is the milestone of amyotrophic lateral sclerosis (ALS). Therefore, morphological analysis along decades focussed on motor neuron loss as the sole marker to score disease severity. Recently, non autonomous cell death took a prominent role to explain the need for additional cell types to induce motor neuron ...
Antonio Paparelli +8 more
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BMJ, 2014 A 59 year old man initially presented with weakness in his right leg and occasional trips. He had a longstanding history of mild low back pain and had a magnetic resonance image performed under the orthopaedic team that showed some cervical spondylolisthesis sparing the spinal cord.
Aleksandar Radunovic +3 more
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Journal of the Neurological Sciences, 1999
The cell and molecular mechanisms which determine the motor neurone (MN) phenotype are unclear. Tissue culture models offer a unique system for the study of a wide variety of MN features. For instance, since the neurone-astrocyte metabolic interactions play a critical role in the selective MN loss observed in amyotrophic lateral sclerosis (ALS), the ...
V. Silani +4 more
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The cell and molecular mechanisms which determine the motor neurone (MN) phenotype are unclear. Tissue culture models offer a unique system for the study of a wide variety of MN features. For instance, since the neurone-astrocyte metabolic interactions play a critical role in the selective MN loss observed in amyotrophic lateral sclerosis (ALS), the ...
V. Silani +4 more
openaire +3 more sources
International Review of Neurobiology, 1999
Publisher Summary This chapter describes three sensory-to-motor reflexes and their associated central circuits and synapses. The uniquely identifiable neurons comprising these reflex circuits offer an excellent opportunity for investigating detailed molecular mechanisms underlying the development and operation of the central nervous system (CNS ...
James R. Trimarchi +2 more
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Publisher Summary This chapter describes three sensory-to-motor reflexes and their associated central circuits and synapses. The uniquely identifiable neurons comprising these reflex circuits offer an excellent opportunity for investigating detailed molecular mechanisms underlying the development and operation of the central nervous system (CNS ...
James R. Trimarchi +2 more
openaire +3 more sources
Physical Medicine and Rehabilitation Clinics of North America, 2001
Motor neuron disease refers to a spectrum of disorders resulting from degeneration of the upper or lower motor neurons or both. Amyotrophic lateral sclerosis is the most common form of motor neuron disease, in which patients demonstrate evidence of both anterior horn cell (lower motor neuron) and corticospinal tract (upper motor neuron) dysfunction ...
Carlayne E. Jackson, Jeffrey Rosenfeld
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Motor neuron disease refers to a spectrum of disorders resulting from degeneration of the upper or lower motor neurons or both. Amyotrophic lateral sclerosis is the most common form of motor neuron disease, in which patients demonstrate evidence of both anterior horn cell (lower motor neuron) and corticospinal tract (upper motor neuron) dysfunction ...
Carlayne E. Jackson, Jeffrey Rosenfeld
openaire +3 more sources
Comprehensive Physiology, 2017
ABSTRACTMotor neurons translate synaptic input from widely distributed premotor networks into patterns of action potentials that orchestrate motor unit force and motor behavior. Intercalated between the CNS and muscles, motor neurons add to and adjust the final motor command.
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ABSTRACTMotor neurons translate synaptic input from widely distributed premotor networks into patterns of action potentials that orchestrate motor unit force and motor behavior. Intercalated between the CNS and muscles, motor neurons add to and adjust the final motor command.
openaire +3 more sources
Journal of the Neurological Sciences, 2014
Allgrove syndrome is a rare autosomal recessive disorder characterised by achalasia, alacrima, adrenal insufficiency, autonomic dysfunction and amyotrophy. The syndrome has been described in childhood and adult presentation, as in our case, is very rare.
Manoj Kumar Goyal +4 more
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Allgrove syndrome is a rare autosomal recessive disorder characterised by achalasia, alacrima, adrenal insufficiency, autonomic dysfunction and amyotrophy. The syndrome has been described in childhood and adult presentation, as in our case, is very rare.
Manoj Kumar Goyal +4 more
openaire +3 more sources