Results 1 to 10 of about 423,991 (315)

Signal processing in complex chemotaxis pathways

Nature Reviews Microbiology, 2011
Steven L Porter, Judith P Armitage
exaly  

Functions and mechanics of dynein motor proteins

Nature Reviews Molecular Cell Biology, 2013
Anthony J Roberts, Takahide Kon
exaly  

Mitochondrial defect in muscle precedes neuromuscular junction degeneration and motor neuron death in CHCHD10S59L/+ mouse

Acta Neuropathologica, 2019
E. Génin, B. Madji Hounoum, S. Bannwarth, K. Fragaki, S. Lacas‐Gervais, Alessandra Mauri-Crouzet, F. Lespinasse, J. Neveu, Baptiste Ropert, Gaëlle Augé, Charlotte Cochaud, Cynthia Lefebvre-Omar, Stéphanie Bigou, Aude Chiot, F. Mochel, S. Boillée, C. Lobsiger, D. Bohl, J. Ricci, V. Paquis-Flucklinger   +19 more
semanticscholar   +1 more source

A motor cortex circuit for motor planning and movement

Nature, 2015
Nuo Li, Tsai-Wen Chen, Zengcai V Guo
exaly  

Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes

Nature Reviews Molecular Cell Biology, 2017
Janet H Iwasa, Bradley R Cairns, Craig L Peterson   +2 more
exaly  

The protein import motor of mitochondria

Nature Reviews Molecular Cell Biology, 2002
exaly  

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

Neuron, 1995
Philip C. Wong, Carlos A. Pardo, David Borchelt, Michael K. Lee, Neal G. Copeland, Nancy A. Jenkins, Sangram S. Sisodia, Don W. Cleveland, Donald L. Price   +8 more
openalex   +2 more sources

Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice

Scientific Reports, 2021
Degeneration and death of motor neurons in Amyotrophic Lateral Sclerosis (ALS) are associated with increased lipid peroxidation. Lipid peroxidation is the driver of ferroptosis, an iron-dependent oxidative mode of cell death.
Liuji Chen, Ren Na, Kirsten Danae McLane, C. S. Thompson, Ju Gao, Xinglong Wang, Qitao Ran   +6 more
semanticscholar   +1 more source

Sumoylation regulates the assembly and activity of the SMN complex

Nature Communications, 2021
Sumoylation is important for the assembly and function of the SMN complex, which plays a central role in RNA processing. Here the authors show that loss of this posttranslational modification impairs the ability of SMN to correct selective deficits in ...
Giulietta M. Riboldi, Irene Faravelli, Takaaki Kuwajima, Nicolas Delestrée, Georgia Dermentzaki, Mariangels De Planell-Saguer, Paola Rinchetti, Le Thi Hao, Christine C. Beattie, Stefania Corti, Serge Przedborski, George Z. Mentis, Francesco Lotti   +12 more
doaj   +1 more source

Redox dysregulation as a driver for DNA damage and its relationship to neurodegenerative diseases

Translational Neurodegeneration, 2023
Redox homeostasis refers to the balance between the production of reactive oxygen species (ROS) as well as reactive nitrogen species (RNS), and their elimination by antioxidants. It is linked to all important cellular activities and oxidative stress is a
Sina Shadfar, Sonam Parakh, Md Shafi Jamali, Julie D. Atkin   +3 more
doaj   +1 more source