Results 241 to 250 of about 423,991 (315)

A Case of Facial-Onset Sensory Motor Neuronopathy - A Rare Variant of Motor Neuron Disease. [PDF]

Ann Indian Acad Neurol
Kumar SP, Haritha S, Sowmini PR, Lakshmanan S, Velayutham SS, Jeyaraj KM, Kannan V, Saravanan RV, Mugundhan K.   +8 more
europepmc   +1 more source

The Nuclear Factor κB–Activator Gene PLEKHG5 Is Mutated in a Form of Autosomal Recessive Lower Motor Neuron Disease with Childhood Onset

, 2007
Isabelle Maystadt, René Rezsöhazy, Martine Barkats, Sandra Duqué, Pascal Vannuffel, Sophie Remacle, Barbara Lambert, Mustapha Najimi, Étienne Sokal, Arnold Munnich, Louis Viollet, Christine Verellen‐Dumoulin   +11 more
openalex   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Impact of the COVID-19 pandemic on the mental and physical wellbeing of patients with motor neuron disease and other neuromuscular disease. [PDF]

Front Neurol
Mazumder S, Carroll AS, Timmins HC, Kiernan MC, Mahoney CJ.   +4 more
europepmc   +1 more source

Messenger RNA Oxidation Occurs Early in Disease Pathogenesis and Promotes Motor Neuron Degeneration in ALS

, 2008
Yueming Chang, Qiongman Kong, Xiu Shan, Guilian Tian, Hristelina Ilieva, Don W. Cleveland, Jeffrey D. Rothstein, David Borchelt, Philip C. Wong, Chien-Liang Lin   +9 more
openalex   +2 more sources

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease

, 2008
Angelo C. Lepore, Britta Rauck, Christine M. Dejea, Andrea C. Pardo, Mahendra S. Rao, Jeffrey D. Rothstein, Nicholas J. Maragakis   +6 more
openalex   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Making Video Games More Inclusive for People Living With Motor Neuron Disease: Scoping Review. [PDF]

JMIR Rehabil Assist Technol
O'Mara B, Harrison M, Harley K, Dwyer N.
europepmc   +1 more source