Results 241 to 250 of about 553,827 (305)

All‐in‐One Analog AI Hardware: On‐Chip Training and Inference with Conductive‐Metal‐Oxide/HfOx ReRAM Devices

Advanced Functional Materials, EarlyView.
An all‐in‐one analog AI accelerator is presented, enabling on‐chip training, weight retention, and long‐term inference acceleration. It leverages a BEOL‐integrated CMO/HfOx ReRAM array with low‐voltage operation (<1.5 V), multi‐bit capability over 32 states, low programming noise (10 nS), and near‐ideal weight transfer.
Donato Francesco Falcone, Victoria Clerico, Wooseok Choi, Tommaso Stecconi, Folkert Horst, Laura Bégon‐Lours, Matteo Galetta, Antonio La Porta, Nikhil Garg, Fabien Alibart, Bert Jan Offrein, Valeria Bragaglia   +11 more
wiley   +1 more source

Muscle fibroblasts and stem cells stimulate motor neurons in an age and exercise-dependent manner. [PDF]

Aging Cell
Soendenbroe C, Schjerling P, Bechshøft CJL, Svensson RB, Schaeffer L, Kjaer M, Chazaud B, Jacquier A, Mackey AL.   +8 more
europepmc   +1 more source

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

Advanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore, Cristiano Pesce, Antonietta Greco, Claudia Pisante, Greta Avancini, Valentina Di Francesco, Yosi Shamay, Paolo Decuzzi   +7 more
wiley   +1 more source

Synaptic loss in motor neurons precipitates age-related dysphagia: Middle agers gotta keep in touch! [PDF]

J Physiol
O'Halloran KD.
europepmc   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source

Tracing motor neurons and primary sensory afferents of the monkey spinal cord with cholera toxin subunit B. [PDF]

Neural Regen Res
He Z, Liu Z, Xu W, Zhang R, Fan S, Wang W, Zheng X.   +6 more
europepmc   +1 more source

Transcriptome-based screening in TARDBP/TDP-43 knock-in motor neurons identifies the NEDD8-activating enzyme inhibitor MLN4924. [PDF]

Sci Rep
Lépine S, Maussion G, Schneider A, Nauleau-Javaudin A, Castellanos-Montiel MJ, Ambriz GJ, Spiegelman D, Abdian N, Franco-Flores AK, Haghi G, Gursu L, Fiorini MR, Dilliott AA, Farhan SMK, Chaineau M, Durcan TM.   +15 more
europepmc   +1 more source

α-Cyclodextrin/Moringin Impacts Actin Cytoskeleton Dynamics with Potential Implications for Synaptic Organization: A Preliminary Transcriptomic Study in NSC-34 Motor Neurons. [PDF]

Int J Mol Sci
Gugliandolo A, Chiricosta L, Calì G, Rollin P, Perenzoni D, Iori R, Mazzon E, D'Angiolini S.   +7 more
europepmc   +1 more source

Ropinirole Functions Through a Dopamine Receptor D2-Independent Mechanism to Ameliorate Amyotrophic Lateral Sclerosis Phenotypes in TARDBP-Mutant iPSC-Derived Motor Neurons. [PDF]

J Neurochem
Asano H, Kawaguchi T, Kato C, Morimoto S, Yano M, Minaguchi M, Yasuda D, Fukushima K, Okano H.   +8 more
europepmc   +1 more source

Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS. [PDF]

Nat Commun
Schweingruber C, Nijssen J, Mechtersheimer J, Reber S, Lebœuf M, O'Brien NL, Mei I, Hedges E, Keuper M, Benitez JA, Radoi V, Jastroch M, Ruepp MD, Hedlund E.   +13 more
europepmc   +1 more source