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Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Neuromodulatory co-expression in cardiac vagal motor neurons of the dorsal motor nucleus of the vagus. [PDF]

iScience
Hornung E, Robbins S, Srivastava A, Achanta S, Chen J, Cheng ZJ, Schwaber J, Vadigepalli R.   +7 more
europepmc   +1 more source

Evolution and development of extraocular motor neurons, nerves and muscles in vertebrates. [PDF]

Ann Anat
Fritzsch B.
europepmc   +1 more source

In vitro analog of operant conditioning in aplysia. II. Modifications of the functional dynamics of an identified neuron contribute to motor pattern selection.

, 1999
Romuald Nargeot, Douglas A. Baxter, John H. Byrne   +2 more
openalex  

n-Butylidenephthalide recovered calcium homeostasis to ameliorate neurodegeneration of motor neurons derived from amyotrophic lateral sclerosis iPSCs. [PDF]

PLoS One
Deng YC, Liu JW, Ting HC, Kuo TC, Chiang CH, Lin EY, Harn HJ, Lin SZ, Chang CY, Chiou TW.   +9 more
europepmc   +1 more source

Synchronous 3D patterning of diverse CNS progenitors generates motor neurons of broad axial identity

Buchner F, Dokuzluoglu Z, Thomas J, Caldarelli A, Kavali S, Rost F, Grass T, Rodríguez-Muela N.   +7 more
europepmc   +1 more source

Kaempferol enhances ER-mitochondria coupling and protects motor neurons from ER stress and mitochondrial dysfunction in C9ORF72- ALS

Pilotto F, Smeele P, Scheidegger O, Diab R, Schobesberger M, Sierra-Delgado JA, Saxena S.   +6 more
europepmc   +1 more source

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Neurons but Motor Neurons in Motor Neuron disease

Italian journal of anatomy and embryology, 2013
The occurrence of motor neuron death is the milestone of amyotrophic lateral sclerosis (ALS). Therefore, morphological analysis along decades focussed on motor neuron loss as the sole marker to score disease severity. Recently, non autonomous cell death took a prominent role to explain the need for additional cell types to induce motor neuron ...
Antonio Paparelli, Antonio Pellegrini, Francesco Fornai, Paola Lenzi, Michela Ferrucci, Stefano Ruggieri, Loredana D'Este, Francesco Giannessi, Lorenzo Fumagalli   +8 more
openaire   +2 more sources

Motor neurone disease [PDF]

BMJ, 2014
A 59 year old man initially presented with weakness in his right leg and occasional trips. He had a longstanding history of mild low back pain and had a magnetic resonance image performed under the orthopaedic team that showed some cervical spondylolisthesis sparing the spinal cord.
Aleksandar Radunovic, Saiji Nageshwaran, Lucy Medina Davies, Imran Rafi   +3 more
openaire   +2 more sources