Results 331 to 340 of about 2,514,411 (397)

Parthenolide regulates microglial and astrocyte function in primary cultures from ALS mice and has neuroprotective effects on primary motor neurons. [PDF]

PLoS One
Thau-Habermann N, Gschwendtberger T, Bodemer C, Petri S.   +3 more
europepmc   +1 more source

Inhibition of Salt-Inducible Kinase 2 Protects Motor Neurons From Degeneration in ALS by Activating Autophagic Flux and Enhancing mTORC1 Activity. [PDF]

CNS Neurosci Ther
Liang W, Zhang C, Wang D, Su X, Tan X, Yang Y, Cong C, Wang Y, Huo D, Wang H, Wang S, Wang X, Feng H.   +12 more
europepmc   +1 more source

Adaptations in common synaptic inputs to spinal motor neurons during grasping versus a less functional hand task

Cabral HV, Cosentino C, Rizzardi A, Inglis JG, Fuglevand AJ, Negro F.   +5 more
europepmc   +1 more source

Synchronous 3D patterning of diverse CNS progenitors generates motor neurons of broad axial identity

Buchner F, Dokuzluoglu Z, Thomas J, Caldarelli A, Kavali S, Rost F, Grass T, Rodríguez-Muela N.   +7 more
europepmc   +1 more source

Evaluation of a biomarker for amyotrophic lateral sclerosis derived from a hypomethylated DNA signature of human motor neurons

Harvey C, Nowak A, Zhang S, Moll T, Weimer AK, Barcons AM, Souza CDS, Ferraiuolo L, Kenna K, Zaitlen N, Caggiano C, Shaw PJ, Snyder MP, Mill J, Hannon E, Cooper-Knock J.   +15 more
europepmc   +1 more source

Kaempferol enhances ER-mitochondria coupling and protects motor neurons from ER stress and mitochondrial dysfunction in C9ORF72- ALS

Pilotto F, Smeele P, Scheidegger O, Diab R, Schobesberger M, Sierra-Delgado JA, Saxena S.   +6 more
europepmc   +1 more source

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Motor Neurons.

Comprehensive Physiology, 2017
Motor neurons translate synaptic input from widely distributed premotor networks into patterns of action potentials that orchestrate motor unit force and motor behavior.
J. Hounsgaard
semanticscholar   +4 more sources

Neurons other than motor neurons in motor neuron disease.

Histology and histopathology, 2017
Amyotrophic lateral sclerosis (ALS) is typically defined by a loss of motor neurons in the central nervous system. Accordingly, morphological analysis for decades considered motor neurons (in the cortex, brainstem and spinal cord) as the neuronal population selectively involved in ALS.
R. Ruffoli, F. Biagioni, C. Busceti, A. Gaglione, L. Ryskalin, S. Gambardella, A. Frati, F. Fornai   +7 more
semanticscholar   +6 more sources

Motor Neuron Disease

The Neurologist, 2009
In order to evaluate the prognosis and possible prognostic factors associated with a bening course, 118 cases of motor neuron disease diagnosed 1948-1975 were followed up. Survival curves, based on the actuarial method showed a survival rate of 18.7 per cent (95 per cent confidence limits: 11.4-26.0) and 7.6 per cent (95 per cent confidence limits: 2.7-
O, Kristensen, B, Melgaard
openaire   +4 more sources