Results 341 to 350 of about 2,514,411 (397)
Some of the next articles are maybe not open access.
Physical Medicine and Rehabilitation Clinics of North America, 2001
Motor neuron disease refers to a spectrum of disorders resulting from degeneration of the upper or lower motor neurons or both. Amyotrophic lateral sclerosis is the most common form of motor neuron disease, in which patients demonstrate evidence of both anterior horn cell (lower motor neuron) and corticospinal tract (upper motor neuron) dysfunction ...
C E, Jackson, J, Rosenfeld
openaire +2 more sources
Motor neuron disease refers to a spectrum of disorders resulting from degeneration of the upper or lower motor neurons or both. Amyotrophic lateral sclerosis is the most common form of motor neuron disease, in which patients demonstrate evidence of both anterior horn cell (lower motor neuron) and corticospinal tract (upper motor neuron) dysfunction ...
C E, Jackson, J, Rosenfeld
openaire +2 more sources
BMJ, 2014
A 59 year old man initially presented with weakness in his right leg and occasional trips. He had a longstanding history of mild low back pain and had a magnetic resonance image performed under the orthopaedic team that showed some cervical spondylolisthesis sparing the spinal cord.
Saiji, Nageshwaran +3 more
openaire +2 more sources
A 59 year old man initially presented with weakness in his right leg and occasional trips. He had a longstanding history of mild low back pain and had a magnetic resonance image performed under the orthopaedic team that showed some cervical spondylolisthesis sparing the spinal cord.
Saiji, Nageshwaran +3 more
openaire +2 more sources
Neurons but Motor Neurons in Motor Neuron disease
2014The occurrence of motor neuron death is the milestone of amyotrophic lateral sclerosis (ALS). Therefore, morphological analysis along decades focussed on motor neuron loss as the sole marker to score disease severity. Recently, non autonomous cell death took a prominent role to explain the need for additional cell types to induce motor neuron ...
Fornai, Francesco +8 more
openaire +1 more source
Science, 2008
The generation of pluripotent stem cells from an individual patient would enable the large-scale production of the cell types affected by that patient's disease.
John T. Dimos +12 more
semanticscholar +1 more source
The generation of pluripotent stem cells from an individual patient would enable the large-scale production of the cell types affected by that patient's disease.
John T. Dimos +12 more
semanticscholar +1 more source
Journal of the Neurological Sciences, 1999
The cell and molecular mechanisms which determine the motor neurone (MN) phenotype are unclear. Tissue culture models offer a unique system for the study of a wide variety of MN features. For instance, since the neurone-astrocyte metabolic interactions play a critical role in the selective MN loss observed in amyotrophic lateral sclerosis (ALS), the ...
V. Silani +4 more
openaire +2 more sources
The cell and molecular mechanisms which determine the motor neurone (MN) phenotype are unclear. Tissue culture models offer a unique system for the study of a wide variety of MN features. For instance, since the neurone-astrocyte metabolic interactions play a critical role in the selective MN loss observed in amyotrophic lateral sclerosis (ALS), the ...
V. Silani +4 more
openaire +2 more sources
2018
Motor neurone disease (MND) patients exhibit poor gait, balance, and postural control, all of which significantly increases their risk of falling. Falls are frequent in the MND population, and are associated with an increased burden of disease. The complex interplay of both motor and extramotor manifestations in this disease contributes to the ...
Thanuja, Dharmadasa +4 more
openaire +2 more sources
Motor neurone disease (MND) patients exhibit poor gait, balance, and postural control, all of which significantly increases their risk of falling. Falls are frequent in the MND population, and are associated with an increased burden of disease. The complex interplay of both motor and extramotor manifestations in this disease contributes to the ...
Thanuja, Dharmadasa +4 more
openaire +2 more sources
Nursing Standard, 2016
Essential facts Motor neurone disease describes a group of related diseases, affecting the neurones in the brain and spinal cord. Progressive, incurable and life-limiting, MND is rare, with about 1,100 people developing it each year in the UK and up to 5,000 people affected at any one time.
openaire +2 more sources
Essential facts Motor neurone disease describes a group of related diseases, affecting the neurones in the brain and spinal cord. Progressive, incurable and life-limiting, MND is rare, with about 1,100 people developing it each year in the UK and up to 5,000 people affected at any one time.
openaire +2 more sources
Postradiation Motor Neuron Syndrome
Archives of Neurology, 1976We report an unusual case of selective lower motor neuron syndrome (MNS) complicating whole neuraxis radiation therapy. Only three well-documented similar cases have been found in a thorough review of the literature. The syndrome has a stereotyped time course and is self-limited.
C H, Sadowsky, E, Sachs, J, Ochoa
openaire +2 more sources
International Review of Neurobiology, 1999
Publisher Summary This chapter describes three sensory-to-motor reflexes and their associated central circuits and synapses. The uniquely identifiable neurons comprising these reflex circuits offer an excellent opportunity for investigating detailed molecular mechanisms underlying the development and operation of the central nervous system (CNS ...
J R, Trimarchi, P, Jin, R K, Murphey
openaire +2 more sources
Publisher Summary This chapter describes three sensory-to-motor reflexes and their associated central circuits and synapses. The uniquely identifiable neurons comprising these reflex circuits offer an excellent opportunity for investigating detailed molecular mechanisms underlying the development and operation of the central nervous system (CNS ...
J R, Trimarchi, P, Jin, R K, Murphey
openaire +2 more sources
Neurology, 1982
We describe a husband and wife with motor neuron disease. The woman had been ill for 10 years with predominantly upper motor neuron signs when her husband developed progressive muscular atrophy. This is the first known report of sporadic motor neuron disease occurring in both partners of a marriage.
D, Chad +5 more
openaire +2 more sources
We describe a husband and wife with motor neuron disease. The woman had been ill for 10 years with predominantly upper motor neuron signs when her husband developed progressive muscular atrophy. This is the first known report of sporadic motor neuron disease occurring in both partners of a marriage.
D, Chad +5 more
openaire +2 more sources