Results 351 to 360 of about 2,514,411 (397)
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Neurology, 1996
The last 5 years have witnessed a great outgrowth in the number of clinical trials testing neuronal growth factors as potential treatments in ALS. These attempts to prevent motor neuron degeneration in ALS with the use of growth factors have their basis in the profound abilities of these molecules to affect motor neuron survival in experimental animals
J L, Elliott, W D, Snider
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The last 5 years have witnessed a great outgrowth in the number of clinical trials testing neuronal growth factors as potential treatments in ALS. These attempts to prevent motor neuron degeneration in ALS with the use of growth factors have their basis in the profound abilities of these molecules to affect motor neuron survival in experimental animals
J L, Elliott, W D, Snider
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Reversible Motor Neuron Disease
European Neurology, 1993We investigated a 69-year-old male with a clinical syndrome resembling amyotrophic lateral sclerosis characterized by fasciculation, wasting of the limb muscles and increased deep tendon reflexes in the lower limbs. Electromyographic (EMG) studies showed abundant positive sharp waves and fibrillation potentials with decreased recruitment in the limbs ...
C P, Tsai +6 more
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Motor neurons rely on motor proteins
Trends in Cell Biology, 2004The importance of active axonal transport to the neuron has been highlighted by the recent discoveries that mutations in microtubule motor proteins result in neurodegenerative diseases. Mutations affecting microtubule motor function have been shown to cause hereditary forms of Charcot-Marie-Tooth disease (type 2A), hereditary spastic paraplegia and ...
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Journal of the Neurological Sciences, 2014
Allgrove syndrome is a rare autosomal recessive disorder characterised by achalasia, alacrima, adrenal insufficiency, autonomic dysfunction and amyotrophy. The syndrome has been described in childhood and adult presentation, as in our case, is very rare.
Venugopalan Y, Vishnu +4 more
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Allgrove syndrome is a rare autosomal recessive disorder characterised by achalasia, alacrima, adrenal insufficiency, autonomic dysfunction and amyotrophy. The syndrome has been described in childhood and adult presentation, as in our case, is very rare.
Venugopalan Y, Vishnu +4 more
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Irish Journal of Medical Science, 1964
(1) A ten year old girl was admitted to hospital suffering from upper motor paralysis. (2) Consideration of the signs, symptoms and progress of the case indicates that this was a mild but extensive case of posterior poliomyelitis, restricted to the middle motor neurone, with which the upper motor neurone synapses.
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(1) A ten year old girl was admitted to hospital suffering from upper motor paralysis. (2) Consideration of the signs, symptoms and progress of the case indicates that this was a mild but extensive case of posterior poliomyelitis, restricted to the middle motor neurone, with which the upper motor neurone synapses.
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ACQUIRED MOTOR NEURON DISORDERS
Neurologic Clinics, 1997The acquired motor neuron disorders are a heterogeneous group of conditions in which motor neuron degeneration or dysfunction produces the predominant manifestation of weakness, while the sensory system is clinically spared. The disorders most commonly seen in clinical practice are amyotrophic lateral sclerosis, late manifestations of poliomyelitis ...
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Consolidating motor neuron identity
Trends in Genetics, 2000Motor neurons (MNs) and interneurons are generated in strict temporal and spatial patterns in the spinal cord, each with distinct topographic locations and characteristic axonal projections. Although signals governing dorsoventral patterning of neuronal progenitors in the spinal cord are quite well understood, this is not true of the downstream, fate ...
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Selective motor activation in organelle transport along axons
Nature Reviews Molecular Cell Biology, 2022Sydney E Cason, Erika L F Holzbaur
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Comparative cellular analysis of motor cortex in human, marmoset and mouse
Nature, 2021Trygve E Bakken +2 more
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