Results 151 to 160 of about 3,875,303 (358)

MiniMovers: An initial pilot and feasibility study to investigate the impact of a mobile application on children’s motor skills and parent support for physical development

, 2023
Yajie Zhang, Nalda Wainwright, Jacqueline D. Goodway, Amanda John, Anna J. Stevenson, Kirsty Edwards Thomas, Seán E. Jenkins, Fatma Layas, Kate Piper   +8 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Supporting Young Children’s Physical Development through Tailored Motor Competency Interventions within a School Setting

Children
Background/Objectives: This study investigated how tailored motor competency (MC) interventions within a bespoke Scheme of Work (SOW) can support young children’s physical development (PD) by enhancing fine motor skills (FMS) and gross motor skills (GMS).
Ellie Huggett, Kristy Howells
doaj   +1 more source

Prediction of school-age IQ, academic achievement, and motor skills in children with positional plagiocephaly

, 2020
Erin R. Wallace, Cindy Ola, Brian G. Leroux, Matthew L. Speltz, Brent R. Collett   +4 more
openalex   +2 more sources

RELATIONSHIP OF BREASTFEEDING WITH GROSS AND FINE MOTOR SKILLS DEVELOPMENT IN INFANT 6-12 MONTHS

, 2021
Rukanah Rukanah
openalex   +2 more sources

Effect of mental imagery and motor representation strategies on acquisition and retention of shooting skills: a RCT trial [PDF]

, 2022
Amin Amini, Sadeq Porali fatide, Maryam Salehi, Sahar Avazpour, Abdolkarin ghabelnezam   +4 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Early Childhood Education in Buffalo, New York [PDF]

, 2008
The National Association for the Education of Young Children (NAEYC) defines early childhood education as the learning experience of a child from birth to age eight.
Connelly, Caitlin M
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The impact of 8 weeks of Heidelberg Ballschule games on the motor proficiency and visual-motor skills of 7-9 year-old female students

International Journal of Adolescence and Youth
The study investigated the effects of Heidelberg Ballschule motor proficiency and visual-motor skills of 7–9 year-old girls. A sample of 30 girls participated in a semi-experimental study, with pre-test and post-test evaluations conducted.
Samira Jafari, Ayoob Sabaghi, Behrooz Ebrahimi   +2 more
doaj   +1 more source