Results 131 to 140 of about 143,556 (259)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Pilot Implementation of an Intervention Program to Promote Fine Motor Skills in Preschoolers: Feasibility and Acceptability. [PDF]

Occup Ther Int
Lersilp S, Panyo K, Chaimaha N, Putthinoi S, Punyakaew A, Sung-U S.   +5 more
europepmc   +1 more source

Learning of motor skill in preteens

, 2013
Time distribution of training/practice as an optimizing parameter has been studied and analyzed. The results obtained were designed to clarify a debate that has been running for more than a century: many authors support the idea that concentrating practice over a short time is more successful, while others state the opposite.
openaire   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Author Correction: Match running performance preceding scoring and conceding a goal in men’s professional soccer

Scientific Reports
Marek Konefał, Błażej Szmigiel, Bogdan Bochenek, Ryland Morgans, Piotr Żmijewski   +4 more
doaj   +1 more source

Fundamental Motor Skills and Motor Competence in Children and Adolescents with Autism Spectrum Disorder (ASD): A Narrative Review. [PDF]

Children (Basel)
Asonitou K, Kottara M, Charitou S, Koutsouki D.   +3 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Longitudinal trajectory of gross motor skills in school-aged children with Rett syndrome. [PDF]

Front Neurol
Bisgaard AM, Wong K, Højfeldt AK, Stahlhut M, Downs J.   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Effects of Exergame-Based Interventions on Executive Functions and Motor Skills in Children with Autism Spectrum Disorder: A Systematic Review. [PDF]

Sports (Basel)
Vigil-Torres N, Carcelén-Fraile MDC, Martínez-Redecillas T, Cecic-Mladinic D.   +3 more
europepmc   +1 more source