Results 111 to 120 of about 3,065,140 (299)
, 2011 This unit contains a PowerPoint presentation about assessing key skills, with explanatory notes, and an audio recording of the two authors talking through the presentation.
Dr Rosalind Duhs +3 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Application of Motor Development Scale: an integrative review
Revista CEFACObjective: to know, understand, and analyze studies that employed the Motor Development Scale as a method for motor evaluation. Methods: the study included the databases Scielo, Pubmed, Lilacs, Science Direct, Web of Science, Scopus and Cochrane to ...
Maria Cecilia Souza Santos +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Universal Strategies to support motor and functional skills in a sample of UK schools
, 2015 Purpose Many children start school with delayed motor development and poor functional skills. Evidence indicates that schools should intervene early to support children’s development, benefiting motor and cognitive domains.
Soan, S., Hutton, E.
core
PILOT STUDY ON INFANT SWIMMING CLASSES AND EARLY MOTOR DEVELOPMENT
, 2015 Alberta Infant Motor Scale (AIMS) scores were examined before and after four months of swimming classes in 12 babies (ages 7 to 9 mo.) assigned to Experimental (n = 6) and Control (n = 6) groups matched on age and developmental status.
Manoel, ED +3 more
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
The Impact of Social Context on Motor, Cognitive, and Affective Behaviors: A Pilot Study Among Physical Education Students [PDF]
Annals of Applied Sport ScienceBackground. In sports and physical education, success requires a range of competencies. Structuring activities within a cooperative or competitive social context can enhance motivation and performance. Objectives.
Maha Mnif +7 more
doaj