Results 101 to 110 of about 3,177,616 (255)

Universal Strategies to support motor and functional skills in a sample of UK schools

open access: yes, 2015
Purpose Many children start school with delayed motor development and poor functional skills. Evidence indicates that schools should intervene early to support children’s development, benefiting motor and cognitive domains.
Soan, S., Hutton, E.
core  

Performance Skills: Motor, Process, and Social Interaction

open access: yes
Performance skills are the actions that are observable elements of an occupation. Occupational therapists analyze how people carry out their activities, often through observation, with the aim of enhancing their participation and satisfaction in life ...
Liu, KPY   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Standardization of Neuromuscular Reflex Analysis—Role of Fine-Tuned Vision-Language Model Consortium and OpenAI gpt-oss Reasoning LLM-Enabled Decision Support System

open access: yesBiomechanics
Background/Objectives: Accurate assessment of neuromuscular reflexes, such as the Hoffmann reflex (H-reflex), plays a critical role in sports science, rehabilitation, and clinical neurology.
Eranga Bandara   +12 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Bureau of Motor Vehicles facts and figures

open access: yes, 2000
Annual; Electronic coverage as of Mar. 1, 2004: 2000-; Title from caption (viewed Mar.
Ohio. Bureau of Motor Vehicles.
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Intra-Reliability of a Wearable Near-Infrared Sensor for Monitoring the Intensity of Exercise

open access: yesApplied Sciences
The Q-LAC analyzer, a portable device employing near-infrared spectroscopy (NIRS), was designed to measure muscle oxygen saturation (SmO2) during physical exercise.
Kamil Michalik   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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