Results 81 to 90 of about 143,556 (259)

Application of Motor Development Scale: an integrative review

Revista CEFAC
Objective: to know, understand, and analyze studies that employed the Motor Development Scale as a method for motor evaluation. Methods: the study included the databases Scielo, Pubmed, Lilacs, Science Direct, Web of Science, Scopus and Cochrane to ...
Maria Cecilia Souza Santos, Suraya Gomes Novais Shimano, Larissa Giovanna de Oliveira Araújo, Karina Pereira   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Subjective vs Objective Evaluation of Knee Stability in Patients before and after Anterior Cruciate Ligament Reconstruction

Central European Journal of Sport Sciences and Medicine, 2014
Every year, the number of anterior cruciate ligament ruptures increases considerably. The present analysis compares patients’ subjective sensations after the ACL injury to an objective arthrometric examination. The subjective evaluation of the knee-
Joanna Ficek, Krzysztof Ficek, Grzegorz Juras, Dawid Pawlak, Aleksandra Wysota   +4 more
doaj  

MEANING OF MOTOR SKILLS IN THE FORMATION OF MOTOR SKILLS IN PRESCHOOL CHILDREN

, 2022
The article reveals a study of the motor activity of preschool children with the help of outdoor games. A program has been developed with the proposed dynamics of the development of motor skills in preschool children in the process of physical education classes. The work reveals an increase in the value of the developed methodology for the formation of
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Effectiveness of Motor Therapy on Motor Skills and Bilateral Coordination of Children With Intellectual Disability

Iranian Rehabilitation Journal, 2018
Objectives: Motor therapy plays a key role on the bilateral coordination skills and motor activities of children with Intellectual Disability (ID). The present research aimed to investigate the effectiveness of motor therapy on motor skills and bilateral
Mohammad Ashori, Ghasem Norouzi, Seyyedeh Somayyeh Jalil-Abkenar   +2 more
doaj   +2 more sources