Results 241 to 250 of about 148,167 (311)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Are Motor Skills and Motor Inhibitions Impaired in Tourette Syndrome? A Review

Journal of Experimental Neuroscience, 2015
Navkiran Kalsi, Renata Tambelli, Paola Aceto, Carlo Lai   +3 more
doaj  

The Associations of SUNRISE Product-Oriented Gross Motor Skills With Process-Oriented TGMD-3. [PDF]

J Mot Learn Dev
Spring KE, Staiano AE, Brandon D, Okely AD, Webster EK.   +4 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Assessing fundamental motor skills proficiency in school-based sports physical education programs: implications for talent development. [PDF]

Front Sports Act Living
Makaruk H, Webster EK, Porter J, Makaruk B, Bodasińska A, Zieliński J, Tomaszewski P, Nogal M, Starzak M, Śliwa M, Banaś M, Biegajło M, Chaliburda A, Suchecki B, Molik B, Sadowski J.   +15 more
europepmc   +1 more source

Implementation of the Use of Loose Parts in the Development of Children's Fine Motor Skills at Al-Faqih Islamic Kindergarten, Pilang

Jawia Bahta, Choirun Nisak Aulina
openalex   +1 more source

Fine Motor Skills, Executive Function, and School Readiness in Preschoolers with Externalizing Behavior Problems. [PDF]

Behav Sci (Basel)
Karimi A, Poznanski B, Hart KC, Nelson EL.   +3 more
europepmc   +1 more source

Impact of play-based intervention and parental support on motor skills, behavioral problems, and parenting stress in Japanese children with probable developmental coordination disorder: A randomized controlled trial. [PDF]

PCN Rep
Hatanaka R, Higuchi Y, Takahashi Y, Hisari A, Sakai K, Takeda M.   +5 more
europepmc   +1 more source

Brain volumes are related with motor skills at late childhood in children born extremely preterm. [PDF]

PLoS One
Broström L, Kvanta H, Örtqvist M, Padilla N, Ådén U.   +4 more
europepmc   +1 more source