Results 81 to 90 of about 148,167 (311)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Iranian Rehabilitation Journal, 2018 Objectives: Motor therapy plays a key role on the bilateral coordination skills and motor activities of children with Intellectual Disability (ID). The present research aimed to investigate the effectiveness of motor therapy on motor skills and bilateral
Mohammad Ashori +2 more
doaj +2 more sources
Motor skills of children with autistic spectrum disorder
SHS Web of Conferences, 2016 The contribution contains results of a research of motor skills of children with autistic spectrum disorder. The group of children represents besides major triad of symptoms, also described difficulties in the field of motor skills.
Zikl Pavel +4 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Central European Journal of Sport Sciences and Medicine, 2014 Every year, the number of anterior cruciate ligament ruptures increases considerably. The present analysis compares patients’ subjective sensations after the ACL injury to an objective arthrometric examination. The subjective evaluation of the knee-
Joanna Ficek +4 more
doaj
Effect of Siblings and Type of Delivery on the Development of Motor Skills in the First 48 Months of Life [PDF]
, 2020 Miguel Rebelo +4 more
openalex +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Frontiers in Public HealthObjectiveThe purpose of this study was to examine the relationship between parent ratings of motor skills and executive function (EF) in children with autism spectrum disorder (ASD) in the United States and Taiwan.Materials and methodOne hundred and ...
Ming-Chih Sung +4 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source