Results 41 to 50 of about 17,995,485 (258)

Achilles tendon exhibits distinct transcriptomic changes with increased mitochondrial energy production under lunar gravity

npj Microgravity
Within the musculoskeletal system, the effects of reduced gravity on muscle and bone are well characterized, whereas the role of tendons remains poorly understood.
Taro Kasai, Toshiya Tsubaki, Takumi Matsumoto, Yasuhide Iwanaga, Asuka Terashima, Yasunori Omata, Sakae Tanaka, Taku Saito   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Short-term overloading exercise attenuates articular chondrocyte features partly via synovium–cartilage interactions mediated by inhibin subunit beta A

Scientific Reports
Excessive mechanical loading leads to cartilage degeneration. However, short-term responses of the synovium and cartilage to overloading and interactions between these tissues remain poorly understood.
Yusuke Arino, Asuka Terashima, Toshiya Tsubaki, Yasuhide Iwanaga, Yasunori Omata, Sakae Tanaka, Taku Saito   +6 more
doaj   +1 more source

Driving Simulator for Electric Vehicles Using the Markov Chain Monte Carlo Method and Evaluation of the Demand Response Effect in Residential Houses

IEEE Access, 2020
It is essential to secure flexible resources in power systems to increase the proportion of variable renewable energy generation systems. One flexible resource is demand response (DR) of the batteries of electric vehicles (EVs). In this study, we propose
Yumiko Iwafune, Kazuhiko Ogimoto, Yuki Kobayashi, Kensuke Murai   +3 more
doaj   +1 more source

The superficial zone of articular cartilage

Inflammation and Regeneration, 2022
The superficial zone of articular cartilage contributes to smooth joint motion through the production of proteoglycan 4 (PRG4), also known as lubricin.
Taku Saito
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Association Between Lateral Femoral Condyle Height and Depth Ratio, Medial Tibial Plateau Slope, and Isolated Posterior Cruciate Ligament Rupture

Orthopaedic Journal of Sports Medicine
Background: The morphological features of the femoral condyles have recently attracted attention as a potential risk factor for knee injuries. However, little is known about whether the femoral condylar morphology is related to posterior cruciate ...
Kaijie Qiu MD, Canlong Wang MD, Linxiang Cheng MD, Yuxuan Zou MD, Chenchen Zhao MD, Zhaopeng Tang MD, Yang Fei MD, Jia Geng MD, Weiliang Shen MD, PhD, Guang Yang MD, Zongyou Pan MD, PhD   +10 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source