Results 21 to 30 of about 407 (254)
Mapping motor representations in the human cerebellum [PDF]
Brain, 2012 The cerebellum is a major motor structure. However, in humans, its efferent topographical organization remains controversial and indirectly inferred from neuroimaging and animal studies. Even central questions such as 'Can we evoke limb movements by stimulating the cerebellar cortex?' have no clear answer.
Mottolese, Carmine +5 more
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The Journal of Cell Biology, 2006 When the protein dynein was discovered to provide the flagellar bending force to axonemal microtubules (MTs) (Gibbons, 1963), “people had jumped to the reasonable hypothesis that dynein was perhaps also involved in other microtubule movements,” recalls Richard Vallee (Columbia University Medical Center, New York, NY).
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Visual Space Constructed by Saccade Motor Maps [PDF]
Frontiers in Human Neuroscience, 2016 How visual space is represented in the brain is an open question in neuroscience. Embodiment theories propose that spatial perception is structured by neural motor maps. Especially, maps which code the targets for saccadic eye movements contain a precise representation of external space.
Zimmermann, Eckart, Lappe, Markus
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Dopaminergic Modulation of Motor Maps in Rat Motor Cortex: An In Vivo Study [PDF]
Neuroscience, 2009 While the primary motor cortex (M1) is know to receive dopaminergic projections, the functional role of these projections is poorly characterized. Here, it is hypothesized that dopaminergic signals modulate M1 excitability and somatotopy, two features of the M1 network relevant for movement execution and learning.
Hosp, J A +4 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Death on the roads : motoring with Agatha Christie [PDF]
Over the course of her autobiography, Agatha Christie makes some fascinating observations about cars, and what their growing ubiquity meant to a young woman transitioning from Victorian girlhood to interwar modernity.
Plain, Gill
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Overlapping Structures in Sensory-Motor Mappings
PLoS ONE, 2014 This paper examines a biologically-inspired representation technique designed for the support of sensory-motor learning in developmental robotics. An interesting feature of the many topographic neural sheets in the brain is that closely packed receptive fields must overlap in order to fully cover a spatial region.
Earland, K., Lee, M., Shaw, P., Law, J.
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Achieving genuinely dynamic road user charging : issues with a GNSS-based approach
, 2014 Peer ...
Pangbourne, Kate +3 more
core +1 more source