Results 261 to 270 of about 3,039,643 (308)
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Methods, 2011
Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which ...
Helmut, Fuchs +49 more
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Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which ...
Helmut, Fuchs +49 more
openaire +2 more sources
The Journal of Immunology, 1976
Abstract The addition of PHA to C3H mouse spleen cells in tissue culture led to the production of lymphotoxin (LT). Cytotoxicity was assayed by addition of the culture fluids to syngeneic target cells labeled with tritiated thymidine; after an incubation period of 72 hr the amount of radioactivity released into the supernatant was ...
G, Trivers, D, Braungart, E J, Leonard
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Abstract The addition of PHA to C3H mouse spleen cells in tissue culture led to the production of lymphotoxin (LT). Cytotoxicity was assayed by addition of the culture fluids to syngeneic target cells labeled with tritiated thymidine; after an incubation period of 72 hr the amount of radioactivity released into the supernatant was ...
G, Trivers, D, Braungart, E J, Leonard
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Science, 1998
Techwire Using the URL at the end of this item, readers can immediately offer feedback and suggestions on this topic. There is a powerful force sweeping through much of biological science: Automation[[HN1][1]].
R, Sikorski, R, Peters
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Techwire Using the URL at the end of this item, readers can immediately offer feedback and suggestions on this topic. There is a powerful force sweeping through much of biological science: Automation[[HN1][1]].
R, Sikorski, R, Peters
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Nature, 1973
In vitro treatment of mouse eggs with hyaluronidase can activate them to develop parthenogenetically as well as denuding them of cumulus cells1–4. Activation and subsequent behaviour of the eggs depend on certain defined conditions. Szollosi5 observed morphological changes in unfertilized mouse eggs in vivo after approximately 14 h in the oviduct ...
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In vitro treatment of mouse eggs with hyaluronidase can activate them to develop parthenogenetically as well as denuding them of cumulus cells1–4. Activation and subsequent behaviour of the eggs depend on certain defined conditions. Szollosi5 observed morphological changes in unfertilized mouse eggs in vivo after approximately 14 h in the oviduct ...
openaire +2 more sources
2018
Genotyping is an invaluable tool for identifying organisms carrying genetic variations including insertions and deletions. This method involves the extraction of DNA from animal tissue samples and subsequent amplification of genomic regions of interest by polymerase chain reaction (PCR).
Sandra, Vuong, Paul, Delgado-Olguin
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Genotyping is an invaluable tool for identifying organisms carrying genetic variations including insertions and deletions. This method involves the extraction of DNA from animal tissue samples and subsequent amplification of genomic regions of interest by polymerase chain reaction (PCR).
Sandra, Vuong, Paul, Delgado-Olguin
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Diabetes Research and Clinical Practice, 1994
The NOD mouse was discovered and established as an inbred strain in Japan. It is an excellent animal model for human Type 1 (insulin-dependent) diabetes mellitus in many aspects, including genetics, immunology, virology, and prevention and therapy. The diabetes and/or insulitis is controlled by at least 10 genes and results from the T cell-mediated ...
T, Hanafusa +6 more
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The NOD mouse was discovered and established as an inbred strain in Japan. It is an excellent animal model for human Type 1 (insulin-dependent) diabetes mellitus in many aspects, including genetics, immunology, virology, and prevention and therapy. The diabetes and/or insulitis is controlled by at least 10 genes and results from the T cell-mediated ...
T, Hanafusa +6 more
openaire +2 more sources
Current Protocols in Mouse Biology, 2015
AbstractNecropsy (also known as autopsy) is the post‐mortem dissection of bodies after euthanasia or death and is a scientific examination conducted to observe and dissect the organs, collect tissues, and determine the extent of grossly evident disease. Research necropsies are conducted to obtain specific samples tailored according to study objectives.
Piper M, Treuting, Jessica M, Snyder
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AbstractNecropsy (also known as autopsy) is the post‐mortem dissection of bodies after euthanasia or death and is a scientific examination conducted to observe and dissect the organs, collect tissues, and determine the extent of grossly evident disease. Research necropsies are conducted to obtain specific samples tailored according to study objectives.
Piper M, Treuting, Jessica M, Snyder
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Blood, 2009
Abstract In this issue of Blood, ter Brugge and colleagues describe the results of their efforts to express SV40 T antigen in mature B cells of mice.1 As a consequence of T antigen expression, B cells develop normally but, upon aging, mice show an accumulation of monoclonal CD5+ B cells and have a chronic lymphocytic leukemia-like ...
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Abstract In this issue of Blood, ter Brugge and colleagues describe the results of their efforts to express SV40 T antigen in mature B cells of mice.1 As a consequence of T antigen expression, B cells develop normally but, upon aging, mice show an accumulation of monoclonal CD5+ B cells and have a chronic lymphocytic leukemia-like ...
openaire +2 more sources
Journal of Dental Education, 2015
Some days, assessment seems like a cat-and-mouse game in a never-ending contest between educators and students. As the fall semester begins and quizzes, midterms, and finals line up ahead of us like racing cars on a track, we are reminded that assessment not only evaluates student performance ...
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Some days, assessment seems like a cat-and-mouse game in a never-ending contest between educators and students. As the fall semester begins and quizzes, midterms, and finals line up ahead of us like racing cars on a track, we are reminded that assessment not only evaluates student performance ...
openaire +2 more sources