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Mouse Proteinuria

American Journal of Physiology-Legacy Content, 1957
Normal adult male mice of various strains excreted 0.6–3.1 mg of urinary protein N/day; females, considerably less. Electrophoretic measurements showed the protein to consist of three components, all having negative mobilities (–7.5 to –8.3 cm2/volt/sec x 10–5 at ph 8.5) greater than that of mouse serum albumin (–6.3 ± 0.1 cm2/ volt/sec.
J S, Finlayson, C A, Baumann
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Mouse phenotyping

Methods, 2011
Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which ...
Helmut, Fuchs   +49 more
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Mouse Lymphotoxin

The Journal of Immunology, 1976
Abstract The addition of PHA to C3H mouse spleen cells in tissue culture led to the production of lymphotoxin (LT). Cytotoxicity was assayed by addition of the culture fluids to syngeneic target cells labeled with tritiated thymidine; after an incubation period of 72 hr the amount of radioactivity released into the supernatant was ...
G, Trivers, D, Braungart, E J, Leonard
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Mouse Genotyping

2018
Genotyping is an invaluable tool for identifying organisms carrying genetic variations including insertions and deletions. This method involves the extraction of DNA from animal tissue samples and subsequent amplification of genomic regions of interest by polymerase chain reaction (PCR).
Sandra, Vuong, Paul, Delgado-Olguin
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KK mouse

Diabetes Research and Clinical Practice, 1994
The KK mouse strain shows inherently glucose intolerance and insulin resistance. When KK mice become obese by aging, dietary means or other ways, such a chemical diabetic state is changed to overt diabetic state associated with frank hyperglycemia and glucosuria.
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Mighty mouse

Blood, 2009
Abstract In this issue of Blood, ter Brugge and colleagues describe the results of their efforts to express SV40 T antigen in mature B cells of mice.1 As a consequence of T antigen expression, B cells develop normally but, upon aging, mice show an accumulation of monoclonal CD5+ B cells and have a chronic lymphocytic leukemia-like ...
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Mouse Chromosome 18

Mammalian Genome, 1992
As of October 1996, there were 444 loci mapped to Chr 18 in the mouse (Table 1); 110 identified as genes or gene-related sequences and 334 identified as anonymous DNA sequences. Since last year's report, 67 new loci were added; 21 identified as genes and 47 identified as DNA segments.
Johnson, K R, Davisson, M T
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Town Mouse, Country Mouse

1995
Abstract To most people, all small rodents are virtually indistinguishable from each other, and as such, they are lumped together and considered to be mice of one kind or another. In Webster’s Third New International Dictionary, one finds the following definition for a mouse: “any of numerous small rodents typically resembling ...
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Mouse Chromosome 5

Mammalian Genome, 1991
The information about each locus for a chromosome appears on one line of the map. At the left is a small figure of the whole chromosome. A box on the chromosome figure indicates which portion of the chromosome is expanded for view on that page. To the right of the small figure is the corresponding expanded centimorgan scale.
C A, Kozak, D A, Stephenson
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Mouse chromosome 12

Mammalian Genome, 1997
Chromosome (Chr) 12 is a newcomer in the linkage genetics of the mouse. None of the classical linkage groups of the mouse map there, despite the suggested association of Va (LG XVI, now known to map to Chr 3) and the Chr 12 arm of the Rb(8.12)5Bnr Robertsonian chromosome (Cattanach and Moseley 1973). No genes were correctly assigned to Chr 12 until the
P, D'Eustachio, R, Riblet
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