Results 61 to 70 of about 788,210 (304)

Trial of Using Germanium Biotite as Immune Stimulant to Foot and Mouth Disease Virus Vaccine in Cattle

open access: yesJournal of Applied Veterinary Sciences, 2018
This study was established in order to investigate the effect of feeding of germanium biotite (GB) on the immune response of vaccinated calves to FMD trivalent oil vaccine.
Ehab El-Sayed Ibrahim   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Invasive Species Management: Foot-and-Mouth Disease in the U.S. Beef Industry [PDF]

open access: yes
A conceptual bio-economic framework that integrates dynamic epidemiologicaleconomic processes was designed to analyze the effects of invasive species introduction on decision-making in a livestock sector (e.g., production and feeding).
Zhao, Zishun   +2 more
core   +2 more sources

Vaccination against Foot-and-mouth disease : do initial conditions affect its benefit? [PDF]

open access: yes, 2013
When facing incursion of a major livestock infectious disease, the decision to implement a vaccination programme is made at the national level. To make this decision, governments must consider whether the benefits of vaccination are sufficient to ...
Auty, Harriet K.   +30 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Immunomodulatory effect of Isoprinosine on sheep immune response to FMDV [PDF]

open access: yesJournal of Applied Veterinary Sciences
The present study evaluated the immunomodulatory effect of Isoprinosine when incorporated into an oil adjuvanted polyvalent foot and mouth disease (FMD) vaccine and administered to sheep. The investigation was conducted in two phases.
Ehab Ibrahim   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

In vitro and in vivo analyses of co-infections with peste des petits ruminants and capripox vaccine strains

open access: yesVirology Journal, 2021
Background Peste des petits ruminants (PPR) and goat pox (GTP) are two devastating animal epidemic diseases that affect small ruminants. Vaccination is one of the most important measures to prevent and control these two severe infectious diseases ...
Dajun Zhang   +7 more
doaj   +1 more source

Mouth-form plasticity in P. pacificus.

open access: yes, 2020
(A) Mouth structure of wild-type eurystomatous (Eu) morph, wild-type stenostomatous (St) morph, nhr-1 mutant, and nhr-40 mutant. Unlabeled images in two focal planes are shown in S1A Fig. (B) Scanning electron microscopy image of the mouth opening of the
Hanh Witte (273924)   +6 more
core   +1 more source

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