Results 61 to 70 of about 1,832,499 (308)

Brinzolamide/Brimonidine Fixed Combination: Simplifying Glaucoma Treatment Regimens

open access: yesOphthalmology and Therapy, 2018
Introduction To simplify the medical treatment of glaucoma for patients on multiple drops by introducing brinzolamide/brimonidine tartrate fixed combination (BBFC) ophthalmic suspension 1%/0.2% (SIMBRINZA®; Alcon Laboratories, Inc., Fort Worth, TX, USA ...
Reza Moosavi, Ejaz Ansari
doaj   +1 more source

Abstract, emotional and concrete concepts and the activation of mouth-hand effectors [PDF]

open access: yes, 2018
According to embodied and grounded theories, concepts are grounded in sensorimotor systems. The majority of evidence supporting these views concerns concepts referring to objects or actions, while evidence on abstract concepts is more scarce.
Benassi, Mariagrazia   +4 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cultural background modulates how we look at other persons' gaze [PDF]

open access: yes, 2013
The current study investigated the role of cultural norms on the development of face-scanning. British and Japanese adults’ eye movements were recorded while they observed avatar faces moving their mouth, and then their eyes toward or away from the ...
Akechi, H.   +5 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Evaluation of the Protective Efficacy of Foot-and-Mouth Disease Vaccines Against O/CATHAY Topotype Virus in Pigs

open access: yesMicroorganisms
The world is divided into seven regional pools based on the serotype distribution and geographical spread of the foot-and-mouth disease (FMD) virus. The Republic of Korea (ROK) belongs to Pool 1, where serotypes O, A, and Asia1 are endemic. Recently, the
Ye-Ji Kim   +14 more
doaj   +1 more source

Construction, Identification and Analysis of the Interaction Network of African Swine Fever Virus MGF360-9L with Host Proteins

open access: yesViruses, 2021
African swine fever virus (ASFV) is prevalent in many countries and is a contagious and lethal virus that infects pigs, posing a threat to the global pig industry and public health.
Bo Yang   +17 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

D-galacto-D-mannan-mediated Dectin-2 activation orchestrates potent cellular and humoral immunity as a viral vaccine adjuvant

open access: yesFrontiers in Immunology
IntroductionConventional foot-and-mouth disease (FMD) vaccines have been developed to enhance their effectiveness; however, several drawbacks remain, such as slow induction of antibody titers, short-lived immune response, and local side effects at the ...
Hyeong Won Kim   +9 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

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