Results 121 to 130 of about 50,276 (341)

Special Design of Removable Partial Denture Restoration Following Surgical Resection of Mouth Floor Neoplasm [PDF]

, 2017
Yan Dong
openalex   +1 more source

Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5

Advanced Science, EarlyView.
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao, Yuan Fei Li, Fu Kang Yuan, Meng Lu Zhao, Ya Wen Han, Jia Xin Wang, Qi Yang, Han Ying Ye, Yu Cheng Lu, Shao Chin Lee   +9 more
wiley   +1 more source

Association of Socio-Demographic and Clinicopathological Risk Factors with Oral Cancers: A 19-Year Retrospective Study

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2021
Objective: To determine the association of socio-demographic and clinic-pathological risk factors with oral cancer in Kelantan, Malaysia. Material and Methods: A 19-year cross-sectional survey was performed in Hospital Universiti Sains Malaysia (HUSM ...
Paras Ahmad, Anas Imran Arshad, Majid Jehangir, Rizwan Mahmood, Gul Muhammad Shaikh, Mohammad Khursheed Alam, Tang Liszen, Jawaad Ahmed Asif   +7 more
doaj  

A Mitochondria‐Targeted Nanozyme Platform for Multi‐Pathway Tumor Therapy via Ferroptosis and Cuproptosis Regulation

Advanced Science, EarlyView.
This work reports a mitochondria‐targeted nanozyme platform, MIL‐Cu1.8S‐TPP/FA, which induces potent cuproptosis via localized delivery of Cu1.8S nanodots to mitochondria. Surface‐anchoring these nanodots onto MIL‐88B metal‐organic frameworks enhances both passive and active tumor targeting.
Chenguang Liu, Lingxiao Guo, Yuying Cheng, Jingjie Gao, Hanling Pan, Jiayi Zhu, Danting Li, Liqing Jiao, Caiyun Fu   +8 more
wiley   +1 more source

Ocupação e câncer da cavidade oral e orofaringe

Cadernos de Saúde Pública
Estudo caso-controle conduzido para avaliar a associação de exposições ocupacionais e câncer oral e orofaringe na Região Metropolitana de São Paulo. Inclui 325 casos e 468 controles, recrutados por freqüência de sexo e faixa etária, entrevistados entre ...
Magda Andreotti, Aparecida Natália Rodrigues, Luiza Maria Nunes Cardoso, Rejane A. de Oliveira Figueiredo, José Eluf-Neto, Victor Wünsch-Filho   +5 more
doaj  

Trends in cancer mortality in Mexico, 1970-1999 [PDF]

, 2017
Background: Few data on cancer mortality have been published for Mexico over the last few decades. It is therefore of interest to conduct a systematic and updated analysis of cancer mortality in this country. Patients and methods: Age-standardised (world
Bosetti, C., Chatenoud, L., La Vecchia, C., Levi, F., Malvezzi, M., Negri, E., Rodríguez, T.   +6 more
core  

Orosomucoid 1 Ameliorates Temporomandibular Joint Osteoarthritis by Maintaining Cartilage Homeostasis

Advanced Science, EarlyView.
The present study identified the key protein ORM1 through the proteomic analysis of synovial fluid samples from patients with temporomandibular joint osteoarthritis (TMJOA), and demonstrated the important role of ORM1 in maintaining cartilage homeostasis via the suppression of VIM/MAPK/MMP signalling.
Dahe Zhang, Yuxin Zhang, Simo Xia, Lu Chen, Pei Shen, Chi Yang   +5 more
wiley   +1 more source

The CT fish mouth ampulla sign: a highly specific finding in main duct and mixed intraductal papillary mucinous neoplasms [PDF]

, 2019
Tingting Zhang, Timothy J Sadler, Siobhan Whitley, Rebecca Brais, Edmund Godfrey   +4 more
openalex   +1 more source

Contribution of Open Mouth Technique in ¹⁸F-FDG PET/CT Imaging in Patients with Malignant Lip Neoplasm

, 2022
Gözde Mütevelizade, Ceren Sezgın, Yasemın Parlak, Gül Gümüşer, Elvan Sayıt   +4 more
openalex   +1 more source

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

Advanced Science, EarlyView.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu, Ze‐Yu Cai, Qing‐Le Li, Tao Zhang, Xiang‐Yu Chu, Chang Wang, Qing‐Yi Zhang, Rong Qi   +7 more
wiley   +1 more source