Results 61 to 70 of about 93,098 (280)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Zeros of closed 1-forms, homoclinic orbits, and Lusternik - Schnirelman theory

open access: yes, 2001
In this paper we study topological lower bounds on the number of zeros of closed 1-forms without Morse type assumptions. We prove that one may always find a representing closed 1-form having at most one zero.
Farber, Michael
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Mortgaging of movable properties as security for debts, in light of Law no. 11 of 2016 issued by the Palestinian Presidency

open access: yesInternational Review of Law, 2021
In conformity with the Palestinian legislature for the comparative legislative development in the field of in-kind guarantees, taking into account the needs of the current stage in Palestinian life, both economic and social, the legislator enacted a ...
حسين عاهد عيسه
doaj   +2 more sources

Increasing access to credit through reforming secured transactions in the MENA Region [PDF]

open access: yes
This paper provides a comparative summary of secured transactions systems related to the use of movable property as collateral in the MENA region vis a vis international practices in countries with modern secured transactions systems.
Alvarez de la Campa, Alejandro
core  

Movable intersection and bigness criterion [PDF]

open access: yes, 2016
In this note, we give a Morse-type bigness criterion for the difference of two pseudo-effective $(1,1)$-classes by using movable intersections. As an application, we give a Morse-type bigness criterion for the difference of two movable $(n-1,n-1 ...
Xiao, Jian
core  

A new method to test discrete Painlev\'e equations

open access: yes, 1996
Necessary discretization rules to preserve the Painlev\'e property are stated. A new method is added to the discrete Painlev\'e test, which perturbs the continuous limit and generates infinitely many no-log conditions.Comment: 12 pages, no figure ...
Bessis   +38 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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