Results 61 to 70 of about 1,451,363 (293)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The property market in China

open access: yes, 2001
Since the new land tenure system, known as the Land Use Rights system (LUR), was introduced in 1978, there has been significant development in the Chinese property market.
Chan, Nelson, Jia, Shi-Jun
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Mortgaging of movable properties as security for debts, in light of Law no. 11 of 2016 issued by the Palestinian Presidency

open access: yesInternational Review of Law, 2021
In conformity with the Palestinian legislature for the comparative legislative development in the field of in-kind guarantees, taking into account the needs of the current stage in Palestinian life, both economic and social, the legislator enacted a ...
حسين عاهد عيسه
doaj   +2 more sources

The Juridical-Canonical Basis of the Management of Movable and Immovable Ecclesiastical Property [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2023
For the understanding of the management of the ecclesiastical goods, we have to take into consideration both the State laws and Church laws, enacted during the entire period of the two millennium.
Nicolae V. Dura, Catalina Mititelu
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Movable public property

open access: yes, 2015
Les biens publics mobiliers s’entendent comme l’ensemble des biens mobiliers placés dans une relation juridique patrimoniale avec les personnes publiques. Certes, ils se caractérisent par leur mobilité (comme les biens privés mobiliers), c’est-à-dire une
Tarlet, Fanny
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Powers of the National Revenue Administration with regard to temporary attachment of movable property: legislative aspects [PDF]

open access: yes
The amendment of the Act on the National Revenue Administration, in force since 1 January 2022, gave officers the right to temporary seizure of movable property.
Kłosowiak, Miłosz
core   +1 more source

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