Results 121 to 130 of about 1,673,118 (289)

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

01575 MOVE Service Trip

open access: yes
MOVE volunteer poses with a local ...

core  

Estimating the willingness to move within Great Britain: Importance and implications [PDF]

open access: yes
The migration of labour is a mechanism through which local and regional labour market differentials can be reduced. It is likely that this mechanism will assume greater importance in the future so long as government assistance to deprived areas continues
Stephen Drinkwater
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Viability of an educational program for lifestyle changes and an algorithm for the derivation of exercise programs in older people at risk of dependency at primary care: PRICA-POWFRAIL study protocol

open access: yesBMC Geriatrics
Background This manuscript presents the study protocol of the PRICA-POWFRAIL randomized controlled trial. Frailty and pre-frailty are major predictors of functional decline and dependency in older adults, yet the implementation of personalized, scalable,
Verónica Mihaiescu-Ion   +8 more
doaj   +1 more source

01568 MOVE Service Trip

open access: yes
MOVE volunteers working on a house during a service ...

core  

Alternating-move Hotelling with Demand Shocks [PDF]

open access: yes
In this paper an infinite-horizon alternating-move Hotelling model in which consumers are uniformly distributed over the market is considered. In a Markov perfect equilibrium, a seller’s move in any period depends on the price the other seller is ...
Leufkens, Kasper, Peeters, Ronald
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

01493 MOVE Service Trip

open access: yes
MOVE group shot on the deck of a ...

core  

Home - About - Disclaimer - Privacy