Results 101 to 110 of about 1,354,346 (298)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Navigating across disciplines in migration and mobility research : a practical and reflective account

open access: yes
This working paper draws on the experiences of three scholars involved in the research project “Evolving (Im)Mobility Regimes: Migrant Workers’ Entitlement and Precarization in Times of Crisis”, conducted within the framework of the ‘nccr-on the move ...
Łysienia, Maja   +2 more
core   +1 more source

The effectiveness of cryostimulation exposure on sleep and recovery in male athletes: Timing considerations

open access: yesEuropean Journal of Sport Science
The objectives of the study were (i) to evaluate the effects of whole‐body cryostimulation (WBC) after training as an effective tool to improve sleep and recovery and (ii) to determine which exposure schedule for WBC (immediately after training vs.
Coralie Arc‐Chagnaud   +6 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

01489 MOVE Service Trip

open access: yes
MOVE volunteer group photo during a service ...

core  

Making the move: information for families of children with a disability making the move from primary to secondary school [PDF]

open access: yes, 2010
Making the move provides information to help families support their son or daughter with a disability in making the move from primary school to secondary school. The information has been developed from: research findings, focus group meetings held across
Parmenter, Trevor   +3 more
core  

Effects of repeated cryostimulation exposures on sleep quality in swimmers during an intense training period

open access: yesExperimental Physiology
The aim of this study was to evaluate the effects of daily partial body cryostimulation exposures on sleep and recovery parameters in elite swimmers undergoing an intense training period.
Coralie Arc‐Chagnaud   +6 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

01493 MOVE Service Trip

open access: yes
MOVE group shot on the deck of a ...

core  

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