Results 81 to 90 of about 1,354,346 (298)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Long-Distance Agreement in Urdu Infinitival Clauses: A Syntactic Analysis
Wah Academia Journal of Global ReligionsThe aim of the current is to investigate long-distance agreement (LDA) in Urdu infinitive clauses specifically emphasizing on DPs case licensing, agreement, and movement, employing Bošković’s model (2003, 2006, 2007).
Naila Kanwal Dar, Asad Ali
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
, 2018 You Move Me is an audio-visual installation made by three artists of different disciplines in collaboration with the people in two different European towns; Žagarė, Lithuania, and Northampton, UK.
Riggs, Gemma
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Ylipaino ja elämäntilanteen vaikeudet selittävät Move!-tuloksia
, 2022 Liikunnanopetukseen integroitu Move!-fyysisen toimintakyvyn seurantajärjestelmä on kehitetty lasten ja nuorten fyysisen toimintakyvyn tukemiseen. Heikkojen Move!-tulosten taustalla on nuoren kokonaisvaltainen elämäntilanne, mutta erityisesti liiallisen ...
Joensuu, Laura
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source