Results 121 to 130 of about 4,260,963 (301)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Vibration Analysis of Moving Belt
This paper deals with a calculation method of free vibration of the moving belt of which axial tension and bending rigidity are taken into consideration. By considering the moving belt the enough long simply supported beam with two moving rollers, the vibration of the moving belt is considered forced vibration by unknown forces and bending moments at ...
openaire +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Sluicing in Basque: a move-and-delete analysis
In this paper I explore sluicing in Basque, the elliptical phenomenon whereby the interrogative clause is elided, but the wh-remnant is pronounced. Specifically, I address the long-debated question of whether sluicing involves a full-fledged syntactic ...
Irene Macazaga Núñez
doaj +1 more source
Standardisation of Provenance Systems in Service Oriented Architectures --- White Paper
This White Paper presents provenance in computer systems as a mechanism by which business and e-science can undertake compliance validation and analysis of their past processes.
Ibbotson, John, Moreau, Luc
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Rhetorical structure of economics Research Articles’ introductions
Post-graduation students or researchers in different disciplines seek to write and publish research articles for graduation and academic promotion. Consequently, Studies were conducted on writing for research publication purposes; approaches as move ...
Somia Slaim, Hind Amel Mostari
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

