Results 131 to 140 of about 814,443 (314)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Rhetorical structure of economics Research Articles’ introductions
مجلة الآداب و العلوم الإجتماعية, 2019 Post-graduation students or researchers in different disciplines seek to write and publish research articles for graduation and academic promotion. Consequently, Studies were conducted on writing for research publication purposes; approaches as move ...
Somia Slaim, Hind Amel Mostari
doaj
Sluicing in Basque: a move-and-delete analysis
Fontes Linguae VasconumIn this paper I explore sluicing in Basque, the elliptical phenomenon whereby the interrogative clause is elided, but the wh-remnant is pronounced. Specifically, I address the long-debated question of whether sluicing involves a full-fledged syntactic ...
Irene Macazaga Núñez
doaj +1 more source
Reliability analysis of processes with moving cracked material
Applied Mathematical Modelling, 2016 The reliability of processes with moving elastic and isotropic material containing initial cracks is considered in terms of fracture. The material is modelled as a moving plate which is simply supported from two of its sides and subjected to homogeneous tension acting in the travelling direction.
openaire +4 more sources
To move or not to move: Is focus on the edge?
A discourse-syntax interface-based approach to three types of focus – Information Focus, Corrective or Contrastive Focus, and Mirative Focus – is discussed in this paper. In my approach, I address the role of discourse/agreement features in the syntactic
Jiménez Fernández, Ángel Luis
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Effective writing appears to be vital in the academic world, as it determines benefits offered to its members (Bhatia, 1993; Hawk & Shah, 2014). In the academic genre of teaching statements (TSs), writing plays a critical role in informing decisions ...
Alhudithi, Ella
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Understanding China's move into Africa : an empirical analysis
, 2009 Published online: 3 February 2009An important new issue on the international scene is the upsurge in market and non-market South–South relations. The aim of this paper is to understand the dynamics that lie behind the recent Chinese move into Africa by ...
SANFILIPPO, Marco, BIGGERI, Mario
core +1 more source